2OVP

Structure of the Skp1-Fbw7 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006511	biological_process	ubiquitin-dependent protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IISGstDrTLKVWNA

Chain	Residue	Details
B	ILE2434-ALA2448
B	VAL2474-ILE2488
B	VAL2554-VAL2568
B	LEU2594-ILE2608
B	VAL2637-LEU2651

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	46
Details	Domain: {"description":"F-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00080","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	40
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	36
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	39
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	36
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	39
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	38
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

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site_id	SWS_FT_FI10
Number of Residues	37
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1g72

Chain	Residue	Details
B	SER2407

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1g72

Chain	Residue	Details
B	ASP2567

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