2OUD

Crystal structure of the catalytic domain of human MKP5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006470	biological_process	protein dephosphorylation
A	0016311	biological_process	dephosphorylation
A	0017017	molecular_function	MAP kinase tyrosine/serine/threonine phosphatase activity

Functional Information from PROSITE/UniProt

site_id	PS00383
Number of Residues	11
Details	TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCqaGvsRSA

Chain	Residue	Details
A	ILE406-ALA416

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	143
Details	Domain: {"description":"Tyrosine-protein phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16806267","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"17400920","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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