2OSA

The Rho-GAP domain of human N-chimaerin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005096	molecular_function	GTPase activator activity
A	0007165	biological_process	signal transduction
A	0043547	biological_process	positive regulation of GTPase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	191
Details	Domain: {"description":"Rho-GAP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Arginine finger; crucial for GTP hydrolysis by stabilizing the transition state","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P30337","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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