2OQP

Solution structure of human interleukin-21

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001819	biological_process	positive regulation of cytokine production
A	0002314	biological_process	germinal center B cell differentiation
A	0002639	biological_process	positive regulation of immunoglobulin production
A	0005125	molecular_function	cytokine activity
A	0005126	molecular_function	cytokine receptor binding
A	0005134	molecular_function	interleukin-2 receptor binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006952	biological_process	defense response
A	0006955	biological_process	immune response
A	0007165	biological_process	signal transduction
A	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
A	0007260	biological_process	tyrosine phosphorylation of STAT protein
A	0008284	biological_process	positive regulation of cell population proliferation
A	0009615	biological_process	response to virus
A	0016064	biological_process	immunoglobulin mediated immune response
A	0030101	biological_process	natural killer cell activation
A	0030890	biological_process	positive regulation of B cell proliferation
A	0032729	biological_process	positive regulation of type II interferon production
A	0032740	biological_process	positive regulation of interleukin-17 production
A	0034105	biological_process	positive regulation of tissue remodeling
A	0042102	biological_process	positive regulation of T cell proliferation
A	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
A	0045954	biological_process	positive regulation of natural killer cell mediated cytotoxicity
A	0048468	biological_process	cell development
A	0048469	biological_process	cell maturation
A	0050729	biological_process	positive regulation of inflammatory response
A	0051251	biological_process	positive regulation of lymphocyte activation
A	0051607	biological_process	defense response to virus
A	0061470	biological_process	T follicular helper cell differentiation
A	0098586	biological_process	cellular response to virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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