Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000703 | molecular_function | oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0003677 | molecular_function | DNA binding |
A | 0003684 | molecular_function | damaged DNA binding |
A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
A | 0006281 | biological_process | DNA repair |
A | 0006284 | biological_process | base-excision repair |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
A | 0016829 | molecular_function | lyase activity |
A | 0019104 | molecular_function | DNA N-glycosylase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 501 |
Chain | Residue |
A | CYS237 |
A | CYS240 |
A | CYS257 |
A | CYS260 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 601 |
Chain | Residue |
A | ARG8 |
A | ASN12 |
A | GLY213 |
A | GLN214 |
A | HOH1220 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 701 |
Chain | Residue |
A | GLN177 |
A | ALA196 |
A | ALA200 |
A | GLU203 |
A | HOH1137 |
A | HOH1166 |
A | HOH1176 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL C 702 |
Chain | Residue |
B | DA407 |
C | DG424 |
C | DG425 |
C | DA426 |
C | HOH1050 |
C | HOH1070 |
C | HOH1134 |
C | HOH1163 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 703 |
Chain | Residue |
A | ALA9 |
A | ASN12 |
A | ASN68 |
A | TRP74 |
A | HOH1039 |
A | HOH1153 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 704 |
Chain | Residue |
A | ASP24 |
A | TRP26 |
A | GLN36 |
A | GLY80 |
A | GLU82 |
A | LYS92 |
A | HOH1123 |
site_id | AC8 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE GOL A 705 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 34 |
Details | ZN_FING: FPG-type |
Chain | Residue | Details |
A | LYS228-HIS262 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Schiff-base intermediate with DNA |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor => ECO:0000305 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor; for beta-elimination activity => ECO:0000305 |
Chain | Residue | Details |
A | LYS52 | |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor; for delta-elimination activity => ECO:0000305 |
Chain | Residue | Details |
A | ALA252 | |
Chain | Residue | Details |
A | GLN69 | |
A | ARG124 | |
A | ASN168 | |