Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 501 |
| Chain | Residue |
| B | HIS978 |
| B | ILE1102 |
| B | ASP1120 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE B3P A 301 |
| Chain | Residue |
| A | HOH86 |
| A | HOH294 |
| A | GLU1039 |
| A | GLU1041 |
| A | THR1050 |
| A | ARG1065 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE B3P B 301 |
| Chain | Residue |
| B | GLU1039 |
| B | GLU1041 |
| B | THR1050 |
| B | ARG1065 |
| B | HOH1191 |
| B | HOH1256 |
| B | HOH1371 |
| B | HOH1390 |
| B | HOH1439 |
| B | HOH1441 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 502 |
| Chain | Residue |
| B | TRP1072 |
| B | GLY1076 |
| B | ARG1112 |
| B | GLN1154 |
| B | HOH1229 |
| B | HOH1301 |
| B | HOH1442 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGagRTG |
| Chain | Residue | Details |
| A | VAL1104-GLY1114 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 254 |
| Details | Domain: {"description":"Tyrosine-protein phosphatase 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | GLU1013 | |
| A | CYS1106 | |
| A | ASP1074 | |
| A | HIS1105 | |
| A | ARG1112 | |
| A | THR1113 | |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | GLU1013 | |
| B | CYS1106 | |
| B | ASP1074 | |
| B | HIS1105 | |
| B | ARG1112 | |
| B | THR1113 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | CYS1106 | |
| A | ASP1074 | |
| A | ARG1112 | |
| A | THR1113 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | CYS1106 | |
| B | ASP1074 | |
| B | ARG1112 | |
| B | THR1113 | |
