2OLZ

Structure of human insulin in presence of thiocyanate at pH 7.0

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005179	molecular_function	hormone activity
A	0005576	cellular_component	extracellular region
B	0005179	molecular_function	hormone activity
B	0005576	cellular_component	extracellular region
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
D	0005179	molecular_function	hormone activity
D	0005576	cellular_component	extracellular region
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
F	0005179	molecular_function	hormone activity
F	0005576	cellular_component	extracellular region
G	0005179	molecular_function	hormone activity
G	0005576	cellular_component	extracellular region
H	0005179	molecular_function	hormone activity
H	0005576	cellular_component	extracellular region
I	0005179	molecular_function	hormone activity
I	0005576	cellular_component	extracellular region
J	0005179	molecular_function	hormone activity
J	0005576	cellular_component	extracellular region
K	0005179	molecular_function	hormone activity
K	0005576	cellular_component	extracellular region
L	0005179	molecular_function	hormone activity
L	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 402

Chain	Residue
B	HIS10
B	SCN502
D	HIS10
F	HIS10

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SCN B 502

Chain	Residue
B	HIS10
B	ZN402
D	HIS10
F	HIS10

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 401

Chain	Residue
H	SCN501
J	HIS10
L	HIS10
H	HIS10

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SCN H 501

Chain	Residue
H	LEU6
H	HIS10
H	ZN401
J	LEU6
J	HIS10
L	HIS10

---

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE RCO A 605

Chain	Residue
A	CYS6
A	SER9
A	ILE10
A	CYS11
A	HOH636
B	LEU11
B	ALA14
D	HIS5
H	LEU17

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE RCO C 604

Chain	Residue
C	CYS6
C	SER9
C	ILE10
C	CYS11
C	HOH605
C	HOH625
D	ALA14
F	HIS5
L	LEU17

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE RCO E 602

Chain	Residue
B	HIS5
E	CYS6
E	ILE10
E	CYS11
E	HOH603
F	LEU11
J	LEU17

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE RCO G 603

Chain	Residue
B	LEU17
G	CYS6
G	SER9
G	ILE10
G	CYS11
G	HOH608
H	LEU11
H	ALA14

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE RCO I 606

Chain	Residue
F	LEU17
I	CYS6
I	SER9
I	ILE10
I	CYS11
I	HOH620
J	ALA14
L	HIS5

---

site_id	BC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE RCO K 601

Chain	Residue
D	LEU17
H	HIS5
K	CYS6
K	SER9
K	ILE10
K	CYS11
K	HOH703
L	LEU11
L	ALA14

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL K 701

Chain	Residue
C	ASN18
C	HOH627
H	PHE1
K	THR8
K	SER9
K	HOH702
K	HOH707

---

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCTSiCSlyqLenyC

Chain	Residue	Details
A	CYS6-CYS20

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	Peptide: {"description":"Insulin A chain","featureId":"PRO_0000015821"}

Chain

Residue

Details

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