2OLG

Crystal structure of the serine protease domain of prophenoloxidase activating factor-I in a zymogen form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC

Chain	Residue	Details
A	VAL151-CYS156

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site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScgGDSGGPLL

Chain	Residue	Details
A	ASP309-LEU320

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Charge relay system => ECO:0000255|PROSITE-ProRule:PRU00274

Chain	Residue	Details
A	HIS155
A	ASP220
A	SER315

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:17287215, ECO:0007744|PDB:2OLG

Chain	Residue	Details
A	GLU175
A	ASN177
A	THR180
A	ASP183

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage => ECO:0000269|PubMed:11012672, ECO:0000269|PubMed:9652393, ECO:0000269|PubMed:9839951

Chain	Residue	Details
A	LYS109

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17287215, ECO:0007744|PDB:2OLG

Chain	Residue	Details
A	ASN131

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1a0j

Chain	Residue	Details
A	HIS155
A	ASP220

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1a0j

Chain	Residue	Details
A	GLY316
A	SER315

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1a0j

Chain	Residue	Details
A	GLY313
A	SER315

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site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1a0j

Chain	Residue	Details
A	HIS155
A	SER315
A	ASP220

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site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1a0j

Chain	Residue	Details
A	HIS155
A	GLY316
A	SER315
A	ASP220

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site_id	CSA6
Number of Residues	5
Details	Annotated By Reference To The Literature 1a0j

Chain	Residue	Details
A	HIS155
A	GLY313
A	SER335
A	SER315
A	ASP220

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site_id	CSA7
Number of Residues	4
Details	Annotated By Reference To The Literature 1a0j

Chain	Residue	Details
A	HIS155
A	GLY313
A	SER315
A	ASP220

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