2OL2

High Resolution Structure of Native PCI in Space Group P21

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001972	molecular_function	retinoic acid binding
A	0002020	molecular_function	protease binding
A	0002080	cellular_component	acrosomal membrane
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005515	molecular_function	protein binding
A	0005539	molecular_function	glycosaminoglycan binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006869	biological_process	lipid transport
A	0007283	biological_process	spermatogenesis
A	0007338	biological_process	single fertilization
A	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
A	0008201	molecular_function	heparin binding
A	0009897	cellular_component	external side of plasma membrane
A	0016020	cellular_component	membrane
A	0030414	molecular_function	peptidase inhibitor activity
A	0031012	cellular_component	extracellular matrix
A	0031091	cellular_component	platelet alpha granule
A	0031094	cellular_component	platelet dense tubular network
A	0031210	molecular_function	phosphatidylcholine binding
A	0032190	molecular_function	acrosin binding
A	0032991	cellular_component	protein-containing complex
A	0036024	cellular_component	protein C inhibitor-TMPRSS7 complex
A	0036025	cellular_component	protein C inhibitor-TMPRSS11E complex
A	0036026	cellular_component	protein C inhibitor-PLAT complex
A	0036027	cellular_component	protein C inhibitor-PLAU complex
A	0036028	cellular_component	protein C inhibitor-thrombin complex
A	0036029	cellular_component	protein C inhibitor-KLK3 complex
A	0036030	cellular_component	protein C inhibitor-plasma kallikrein complex
A	0070062	cellular_component	extracellular exosome
A	0070684	biological_process	seminal clot liquefaction
A	0097181	cellular_component	protein C inhibitor-coagulation factor V complex
A	0097182	cellular_component	protein C inhibitor-coagulation factor Xa complex
A	0097183	cellular_component	protein C inhibitor-coagulation factor XI complex
B	0001972	molecular_function	retinoic acid binding
B	0002020	molecular_function	protease binding
B	0002080	cellular_component	acrosomal membrane
B	0004867	molecular_function	serine-type endopeptidase inhibitor activity
B	0005515	molecular_function	protein binding
B	0005539	molecular_function	glycosaminoglycan binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006869	biological_process	lipid transport
B	0007283	biological_process	spermatogenesis
B	0007338	biological_process	single fertilization
B	0007342	biological_process	fusion of sperm to egg plasma membrane involved in single fertilization
B	0008201	molecular_function	heparin binding
B	0009897	cellular_component	external side of plasma membrane
B	0016020	cellular_component	membrane
B	0030414	molecular_function	peptidase inhibitor activity
B	0031012	cellular_component	extracellular matrix
B	0031091	cellular_component	platelet alpha granule
B	0031094	cellular_component	platelet dense tubular network
B	0031210	molecular_function	phosphatidylcholine binding
B	0032190	molecular_function	acrosin binding
B	0032991	cellular_component	protein-containing complex
B	0036024	cellular_component	protein C inhibitor-TMPRSS7 complex
B	0036025	cellular_component	protein C inhibitor-TMPRSS11E complex
B	0036026	cellular_component	protein C inhibitor-PLAT complex
B	0036027	cellular_component	protein C inhibitor-PLAU complex
B	0036028	cellular_component	protein C inhibitor-thrombin complex
B	0036029	cellular_component	protein C inhibitor-KLK3 complex
B	0036030	cellular_component	protein C inhibitor-plasma kallikrein complex
B	0070062	cellular_component	extracellular exosome
B	0070684	biological_process	seminal clot liquefaction
B	0097181	cellular_component	protein C inhibitor-coagulation factor V complex
B	0097182	cellular_component	protein C inhibitor-coagulation factor Xa complex
B	0097183	cellular_component	protein C inhibitor-coagulation factor XI complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 650

Chain	Residue
A	LEU37
A	ALA40
A	ALA41
A	ASN45
A	ILE46
A	TYR293
A	HOH664
A	HOH735

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Functional Information from PROSITE/UniProt

site_id	PS00284
Number of Residues	11
Details	SERPIN Serpins signature. LVFNRPFLMfI

Chain	Residue	Details
A	LEU363-ILE373

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Site: {"description":"Reactive bond"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18467335","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12575940","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18467335","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18467335","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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