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2OL2

High Resolution Structure of Native PCI in Space Group P21

Functional Information from GO Data
ChainGOidnamespacecontents
A0001972molecular_functionretinoic acid binding
A0002020molecular_functionprotease binding
A0002080cellular_componentacrosomal membrane
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005539molecular_functionglycosaminoglycan binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006869biological_processlipid transport
A0007283biological_processspermatogenesis
A0007338biological_processsingle fertilization
A0007342biological_processfusion of sperm to egg plasma membrane involved in single fertilization
A0008201molecular_functionheparin binding
A0009897cellular_componentexternal side of plasma membrane
A0016020cellular_componentmembrane
A0031091cellular_componentplatelet alpha granule
A0031094cellular_componentplatelet dense tubular network
A0031210molecular_functionphosphatidylcholine binding
A0032190molecular_functionacrosin binding
A0032991cellular_componentprotein-containing complex
A0036024cellular_componentprotein C inhibitor-TMPRSS7 complex
A0036025cellular_componentprotein C inhibitor-TMPRSS11E complex
A0036026cellular_componentprotein C inhibitor-PLAT complex
A0036027cellular_componentprotein C inhibitor-PLAU complex
A0036028cellular_componentprotein C inhibitor-thrombin complex
A0036029cellular_componentprotein C inhibitor-KLK3 complex
A0036030cellular_componentprotein C inhibitor-plasma kallikrein complex
A0051346biological_processnegative regulation of hydrolase activity
A0062023cellular_componentcollagen-containing extracellular matrix
A0070062cellular_componentextracellular exosome
A0097181cellular_componentprotein C inhibitor-coagulation factor V complex
A0097182cellular_componentprotein C inhibitor-coagulation factor Xa complex
A0097183cellular_componentprotein C inhibitor-coagulation factor XI complex
B0001972molecular_functionretinoic acid binding
B0002020molecular_functionprotease binding
B0002080cellular_componentacrosomal membrane
B0004867molecular_functionserine-type endopeptidase inhibitor activity
B0005515molecular_functionprotein binding
B0005539molecular_functionglycosaminoglycan binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006869biological_processlipid transport
B0007283biological_processspermatogenesis
B0007338biological_processsingle fertilization
B0007342biological_processfusion of sperm to egg plasma membrane involved in single fertilization
B0008201molecular_functionheparin binding
B0009897cellular_componentexternal side of plasma membrane
B0016020cellular_componentmembrane
B0031091cellular_componentplatelet alpha granule
B0031094cellular_componentplatelet dense tubular network
B0031210molecular_functionphosphatidylcholine binding
B0032190molecular_functionacrosin binding
B0032991cellular_componentprotein-containing complex
B0036024cellular_componentprotein C inhibitor-TMPRSS7 complex
B0036025cellular_componentprotein C inhibitor-TMPRSS11E complex
B0036026cellular_componentprotein C inhibitor-PLAT complex
B0036027cellular_componentprotein C inhibitor-PLAU complex
B0036028cellular_componentprotein C inhibitor-thrombin complex
B0036029cellular_componentprotein C inhibitor-KLK3 complex
B0036030cellular_componentprotein C inhibitor-plasma kallikrein complex
B0051346biological_processnegative regulation of hydrolase activity
B0062023cellular_componentcollagen-containing extracellular matrix
B0070062cellular_componentextracellular exosome
B0097181cellular_componentprotein C inhibitor-coagulation factor V complex
B0097182cellular_componentprotein C inhibitor-coagulation factor Xa complex
B0097183cellular_componentprotein C inhibitor-coagulation factor XI complex
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE GOL A 650
ChainResidue
ALEU37
AALA40
AALA41
AASN45
AILE46
ATYR293
AHOH664
AHOH735

Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. LVFNRPFLMfI
ChainResidueDetails
ALEU363-ILE373

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Reactive bond
ChainResidueDetails
AARG354
BARG354

site_idSWS_FT_FI2
Number of Residues2
DetailsCARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:21056543, ECO:0000269|PubMed:22171320
ChainResidueDetails
ATHR20
BTHR20

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:18467335
ChainResidueDetails
AASN230
BASN230

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12575940, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:18467335
ChainResidueDetails
AASN243
BASN243

site_idSWS_FT_FI5
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:18467335
ChainResidueDetails
AASN319
BASN319

219140

PDB entries from 2024-05-01

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