2OK8

Ferredoxin-NADP+ reductase from Plasmodium falciparum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
B	0016491	molecular_function	oxidoreductase activity
C	0016491	molecular_function	oxidoreductase activity
D	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE FLC B 9001

Chain	Residue
A	LYS267
B	HOH9075
B	HOH9077
C	PHE257
C	TYR258
D	TYR264
A	HIS300
B	TYR218
B	TYR248
B	LYS249
B	GLN250
B	HOH9022
B	HOH9066
B	HOH9070

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FLC A 9002

Chain	Residue
A	ASN275
A	ASN276
A	LYS278
B	GLU220
B	LEU226
B	GLU230
B	TYR244
B	PHE246
B	HOH9044

---

site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FAD A 415

Chain	Residue
A	ARG101
A	LEU102
A	TYR103
A	SER104
A	ALA117
A	ILE118
A	LYS119
A	HIS121
A	TYR123
A	GLY136
A	TYR137
A	CYS138
A	SER139
A	THR180
A	TYR316
A	HOH9006
A	HOH9008
A	HOH9013
A	HOH9018
A	HOH9029
B	LYS13

---

site_id	AC4
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD B 415

Chain	Residue
A	LYS13
B	ARG101
B	LEU102
B	TYR103
B	SER104
B	ALA117
B	ILE118
B	LYS119
B	HIS121
B	TYR123
B	GLY136
B	TYR137
B	CYS138
B	SER139
B	THR180
B	GLU314
B	TYR316
B	HOH9003
B	HOH9004
B	HOH9008
B	HOH9011
B	HOH9034
B	HOH9038
B	HOH9080

---

site_id	AC5
Number of Residues	23
Details	BINDING SITE FOR RESIDUE FAD C 415

Chain	Residue
C	THR53
C	ARG101
C	LEU102
C	TYR103
C	SER104
C	ALA117
C	ILE118
C	LYS119
C	HIS121
C	TYR123
C	GLY136
C	TYR137
C	CYS138
C	SER139
C	THR180
C	TYR316
C	HOH416
C	HOH417
C	HOH419
C	HOH428
C	HOH432
C	HOH470
D	LYS13

---

site_id	AC6
Number of Residues	20
Details	BINDING SITE FOR RESIDUE FAD D 415

Chain	Residue
D	HIS121
D	TYR123
D	GLY136
D	TYR137
D	CYS138
D	SER139
D	THR180
D	TYR316
D	HOH416
D	HOH417
D	HOH420
D	HOH421
C	LYS13
D	ARG101
D	LEU102
D	TYR103
D	SER104
D	ALA117
D	ILE118
D	LYS119

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:17258767, ECO:0007744|PDB:2OK8

Chain	Residue	Details
A	LYS13
B	LYS13
C	LYS13
D	LYS13

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:17258767, ECO:0000269|PubMed:19736991, ECO:0007744|PDB:2OK7, ECO:0007744|PDB:2OK8, ECO:0007744|PDB:3JQP, ECO:0007744|PDB:3JQQ, ECO:0007744|PDB:3JQR

Chain	Residue	Details
A	ALA100
C	ALA117
C	TYR137
C	TYR316
D	ALA100
D	ALA117
D	TYR137
D	TYR316
A	ALA117
A	TYR137
A	TYR316
B	ALA100
B	ALA117
B	TYR137
B	TYR316
C	ALA100

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000305|PubMed:17258767, ECO:0000305|PubMed:19736991, ECO:0007744|PDB:2OK7, ECO:0007744|PDB:3JQP, ECO:0007744|PDB:3JQQ

Chain	Residue	Details
A	LYS119
C	SER247
C	TYR258
C	HIS286
D	LYS119
D	SER247
D	TYR258
D	HIS286
A	SER247
A	TYR258
A	HIS286
B	LYS119
B	SER247
B	TYR258
B	HIS286
C	LYS119

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:19736991, ECO:0007744|PDB:3JQP

Chain	Residue	Details
A	THR180
B	THR180
C	THR180
D	THR180

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305|PubMed:17258767, ECO:0000305|PubMed:19736991, ECO:0007744|PDB:2OK7, ECO:0007744|PDB:3JQP

Chain	Residue	Details
A	VAL217
B	VAL217
C	VAL217
D	VAL217

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:19736991, ECO:0007744|PDB:3JQQ

Chain	Residue	Details
A	LYS287
B	LYS287
C	LYS287
D	LYS287

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
A	SER104
A	GLU314
A	CYS284

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
B	SER104
B	GLU314
B	CYS284

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
C	SER104
C	GLU314
C	CYS284

---

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
D	SER104
D	GLU314
D	CYS284

---

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
A	TYR103

---

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
B	TYR103

---

site_id	CSA7
Number of Residues	1
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
C	TYR103

---

site_id	CSA8
Number of Residues	1
Details	Annotated By Reference To The Literature 1fnb

Chain	Residue	Details
D	TYR103

---