2OHO
Structural Basis for Glutamate Racemase Inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0008881 | molecular_function | glutamate racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| A | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| A | 0071555 | biological_process | cell wall organization |
| B | 0008360 | biological_process | regulation of cell shape |
| B | 0008881 | molecular_function | glutamate racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| B | 0036361 | molecular_function | racemase activity, acting on amino acids and derivatives |
| B | 0071555 | biological_process | cell wall organization |
Functional Information from PROSITE/UniProt
| site_id | PS00924 |
| Number of Residues | 11 |
| Details | ASP_GLU_RACEMASE_2 Aspartate and glutamate racemases signature 2. LVlGCTHYPlL |
| Chain | Residue | Details |
| A | LEU179-LEU189 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:O58403, ECO:0000255|HAMAP-Rule:MF_00258 |
| Chain | Residue | Details |
| A | CYS73 | |
| A | CYS183 | |
| B | CYS73 | |
| B | CYS183 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00258, ECO:0000305|PubMed:17658548 |
| Chain | Residue | Details |
| A | ASP10 | |
| A | ASN74 | |
| B | ASP10 | |
| B | ASN74 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P22634, ECO:0000255|HAMAP-Rule:MF_00258 |
| Chain | Residue | Details |
| A | TYR42 | |
| A | THR184 | |
| B | TYR42 | |
| B | THR184 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1b73 |
| Chain | Residue | Details |
| A | ASP10 | |
| A | CYS183 | |
| A | CYS73 | |
| A | SER11 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1b73 |
| Chain | Residue | Details |
| B | ASP10 | |
| B | CYS183 | |
| B | CYS73 | |
| B | SER11 |
