2OHH
Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, active oxidized state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052765 | molecular_function | coenzyme F420H2 oxidase activity |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052765 | molecular_function | coenzyme F420H2 oxidase activity |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0010181 | molecular_function | FMN binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0052765 | molecular_function | coenzyme F420H2 oxidase activity |
| E | 0009055 | molecular_function | electron transfer activity |
| E | 0010181 | molecular_function | FMN binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0052765 | molecular_function | coenzyme F420H2 oxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 501 |
| Chain | Residue |
| A | ASP87 |
| A | HIS88 |
| A | ASP170 |
| A | HIS233 |
| A | FE502 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 502 |
| Chain | Residue |
| A | FE501 |
| A | HIS83 |
| A | GLU85 |
| A | HIS151 |
| A | ASP170 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B 1501 |
| Chain | Residue |
| B | ASP87 |
| B | HIS88 |
| B | ASP170 |
| B | HIS233 |
| B | FE1502 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B 1502 |
| Chain | Residue |
| B | HIS83 |
| B | GLU85 |
| B | HIS151 |
| B | ASP170 |
| B | FE1501 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE D 2501 |
| Chain | Residue |
| D | ASP87 |
| D | HIS88 |
| D | ASP170 |
| D | HIS233 |
| D | SO42414 |
| D | FE2502 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE D 2502 |
| Chain | Residue |
| D | HIS83 |
| D | GLU85 |
| D | HIS151 |
| D | ASP170 |
| D | SO42414 |
| D | FE2501 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE E 3501 |
| Chain | Residue |
| E | ASP87 |
| E | HIS88 |
| E | ASP170 |
| E | HIS233 |
| E | FE3502 |
| E | HOH3971 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE E 3502 |
| Chain | Residue |
| E | HIS83 |
| E | GLU85 |
| E | HIS151 |
| E | ASP170 |
| E | FE3501 |
| E | HOH3971 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2414 |
| Chain | Residue |
| D | TYR25 |
| D | HIS26 |
| D | GLU85 |
| D | ASP87 |
| D | HIS151 |
| D | ASP170 |
| D | HIS175 |
| D | LEU202 |
| D | HIS233 |
| D | FE2501 |
| D | FE2502 |
| site_id | BC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FMN A 701 |
| Chain | Residue |
| A | THR265 |
| A | MET266 |
| A | HIS267 |
| A | GLY268 |
| A | SER269 |
| A | THR270 |
| A | PRO316 |
| A | THR317 |
| A | ILE318 |
| A | TYR319 |
| A | ASP320 |
| A | SER351 |
| A | MET352 |
| A | GLY353 |
| A | GLY354 |
| A | ASN355 |
| A | GLY356 |
| A | TYR381 |
| A | HOH736 |
| A | HOH887 |
| B | HIS26 |
| B | HIS151 |
| B | TRP152 |
| B | LEU202 |
| B | HOH1716 |
| site_id | BC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FMN B 1701 |
| Chain | Residue |
| B | ASN355 |
| B | GLY356 |
| B | TYR381 |
| B | HOH1728 |
| B | HOH1731 |
| A | GLU85 |
| A | HIS151 |
| A | TRP152 |
| A | LEU202 |
| B | THR265 |
| B | MET266 |
| B | HIS267 |
| B | GLY268 |
| B | SER269 |
| B | THR270 |
| B | PRO316 |
| B | THR317 |
| B | ILE318 |
| B | TYR319 |
| B | ASP320 |
| B | SER351 |
| B | MET352 |
| B | GLY353 |
| B | GLY354 |
| site_id | BC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FMN D 2701 |
| Chain | Residue |
| D | THR265 |
| D | MET266 |
| D | HIS267 |
| D | GLY268 |
| D | SER269 |
| D | THR270 |
| D | PRO316 |
| D | THR317 |
| D | ILE318 |
| D | TYR319 |
| D | ASP320 |
| D | SER351 |
| D | MET352 |
| D | GLY353 |
| D | GLY354 |
| D | ASN355 |
| D | GLY356 |
| D | TYR381 |
| D | HOH2705 |
| D | HOH2793 |
| E | GLU85 |
| E | HIS151 |
| E | TRP152 |
| E | LEU202 |
| site_id | BC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FMN E 3701 |
| Chain | Residue |
| D | GLU85 |
| D | HIS151 |
| D | TRP152 |
| D | LEU202 |
| D | HOH2886 |
| E | THR265 |
| E | MET266 |
| E | HIS267 |
| E | GLY268 |
| E | SER269 |
| E | THR270 |
| E | PRO316 |
| E | THR317 |
| E | ILE318 |
| E | TYR319 |
| E | ASP320 |
| E | SER351 |
| E | MET352 |
| E | GLY353 |
| E | GLY354 |
| E | ASN355 |
| E | GLY356 |
| E | TYR381 |
| E | HOH3730 |
| E | HOH3813 |
Functional Information from PROSITE/UniProt
| site_id | PS00201 |
| Number of Residues | 17 |
| Details | FLAVODOXIN Flavodoxin signature. VIYdTMhGsTRkmAHaI |
| Chain | Residue | Details |
| A | VAL261-ILE277 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 560 |
| Details | Domain: {"description":"Flavodoxin-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00088","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17480207","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 64 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17480207","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17480207","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OHH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| A | ASP87 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| B | ASP87 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| D | ASP87 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| E | ASP87 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| A | ASN201 | |
| A | ASP87 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| B | ASN201 | |
| B | ASP87 |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| D | ASN201 | |
| D | ASP87 |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| E | ASN201 | |
| E | ASP87 |
