Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| A | 0015940 | biological_process | pantothenate biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0050661 | molecular_function | NADP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| B | 0015940 | biological_process | pantothenate biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 801 |
| Chain | Residue |
| B | ALA171 |
| B | LEU227 |
| B | HOH946 |
| site_id | AC2 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAP A 304 |
| Chain | Residue |
| A | LEU30 |
| A | ARG31 |
| A | THR70 |
| A | LEU71 |
| A | LYS72 |
| A | GLN75 |
| A | ALA79 |
| A | HIS97 |
| A | ASN98 |
| A | THR118 |
| A | HIS120 |
| A | ALA121 |
| A | ALA122 |
| A | GLU256 |
| A | HOH712 |
| A | HOH713 |
| A | HOH768 |
| A | HOH769 |
| A | HOH785 |
| A | HOH791 |
| A | HOH796 |
| A | HOH802 |
| A | HOH846 |
| A | HOH868 |
| A | HOH876 |
| A | LEU6 |
| A | GLY7 |
| A | GLY9 |
| A | ALA10 |
| A | LEU11 |
| A | TRP29 |
| site_id | AC3 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE NAP B 802 |
| Chain | Residue |
| B | LEU6 |
| B | GLY7 |
| B | CYS8 |
| B | GLY9 |
| B | ALA10 |
| B | LEU11 |
| B | TRP29 |
| B | LEU30 |
| B | ARG31 |
| B | THR70 |
| B | LEU71 |
| B | LYS72 |
| B | GLN75 |
| B | HIS97 |
| B | ASN98 |
| B | THR118 |
| B | HIS120 |
| B | ALA121 |
| B | ALA122 |
| B | ASN241 |
| B | SER244 |
| B | ARG253 |
| B | GLU256 |
| B | PAF601 |
| B | HOH812 |
| B | HOH834 |
| B | HOH839 |
| B | HOH879 |
| B | HOH885 |
| B | HOH886 |
| B | HOH893 |
| B | HOH913 |
| B | HOH914 |
| B | HOH919 |
| B | HOH941 |
| B | HOH988 |
| B | HOH999 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PAF B 601 |
| Chain | Residue |
| B | ASN98 |
| B | LYS176 |
| B | ASN180 |
| B | ILE183 |
| B | ASN184 |
| B | ASN194 |
| B | ASN241 |
| B | SER243 |
| B | SER244 |
| B | NAP802 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PAF A 602 |
| Chain | Residue |
| A | ASN98 |
| A | ASN180 |
| A | ASN184 |
| A | ASN194 |
| A | VAL234 |
| A | SER243 |
| A | SER244 |
| A | HOH838 |
| A | HOH849 |
| A | HOH853 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DIO A 701 |
| Chain | Residue |
| A | ASP258 |
| A | TYR259 |
| A | ARG266 |
| B | ASN127 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DIO A 702 |
| Chain | Residue |
| B | ASN127 |
| A | GLY262 |
| A | ARG266 |
| A | ARG269 |
| A | HOH731 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DIO B 703 |
| Chain | Residue |
| A | ASP229 |
| A | GLN233 |
| B | LYS21 |
| B | GLU43 |
| B | ASP45 |
| B | SER47 |
| B | HOH869 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DIO B 704 |
| Chain | Residue |
| B | ALA55 |
| B | ASP57 |
| B | TRP190 |
| B | GLU203 |
| B | ARG280 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"11123955","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15966718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17229734","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17229734","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 721 |
| Chain | Residue | Details |
| A | LYS176 | proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 721 |
| Chain | Residue | Details |
| B | LYS176 | proton acceptor, proton donor |
