Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2OEC

Crystal structure of the uridine phosphorylase from Salmonella typhimurium in complex with 2,2'-anhydrouridine and potassium ion at 2.194A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004850	molecular_function	uridine phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0009166	biological_process	nucleotide catabolic process
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0044206	biological_process	UMP salvage
B	0003824	molecular_function	catalytic activity
B	0004850	molecular_function	uridine phosphorylase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009116	biological_process	nucleoside metabolic process
B	0009164	biological_process	nucleoside catabolic process
B	0009166	biological_process	nucleotide catabolic process
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0044206	biological_process	UMP salvage
C	0003824	molecular_function	catalytic activity
C	0004850	molecular_function	uridine phosphorylase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0009116	biological_process	nucleoside metabolic process
C	0009164	biological_process	nucleoside catabolic process
C	0009166	biological_process	nucleotide catabolic process
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0044206	biological_process	UMP salvage
D	0003824	molecular_function	catalytic activity
D	0004850	molecular_function	uridine phosphorylase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0009116	biological_process	nucleoside metabolic process
D	0009164	biological_process	nucleoside catabolic process
D	0009166	biological_process	nucleotide catabolic process
D	0016757	molecular_function	glycosyltransferase activity
D	0016763	molecular_function	pentosyltransferase activity
D	0044206	biological_process	UMP salvage
E	0003824	molecular_function	catalytic activity
E	0004850	molecular_function	uridine phosphorylase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0009116	biological_process	nucleoside metabolic process
E	0009164	biological_process	nucleoside catabolic process
E	0009166	biological_process	nucleotide catabolic process
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
E	0044206	biological_process	UMP salvage
F	0003824	molecular_function	catalytic activity
F	0004850	molecular_function	uridine phosphorylase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0009116	biological_process	nucleoside metabolic process
F	0009164	biological_process	nucleoside catabolic process
F	0009166	biological_process	nucleotide catabolic process
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity
F	0044206	biological_process	UMP salvage

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K C 501

Chain	Residue
C	GLU1049
C	ILE1069
C	SER1073
D	GLU1049
D	ILE1069
D	SER1073

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K E 502

Chain	Residue
F	GLU1049
F	ILE1069
F	SER1073
E	GLU1049
E	ILE1069
E	SER1073

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K A 503

Chain	Residue
A	GLU1049
A	ILE1069
A	SER1073
B	GLU1049
B	ILE1069
B	SER1073

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ANU B 2

Chain	Residue
A	HIS1008
B	ILE1069
B	THR1094
B	GLY1096
B	GLN1166
B	GLU1196
B	MET1197
B	GLU1198
B	HOH1296

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ANU F 6

Chain	Residue
E	HIS1008
F	GOL16
F	THR1094
F	PHE1162
F	GLN1166
F	ARG1168
F	GLU1196
F	MET1197
F	GLU1198
F	HOH1264

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 1PE B 62

Chain	Residue
B	SER1004
B	ASP1005
B	ARG1168
B	VAL1221
B	ASN1222
B	ARG1223
B	GLN1225

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 1PE D 314

Chain	Residue
D	ARG1178
D	LYS1181
D	HOH1293

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 1PE B 315

Chain	Residue
B	ARG1178
B	LYS1181
B	HOH1298
C	ARG1178
E	ARG1178

site_id	AC9
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL F 16

Chain	Residue
E	ARG1048
F	ANU6
F	GLY1026
F	ASP1027
F	ARG1030
F	ARG1091
F	ILE1092
F	GLY1093
F	THR1094
F	GLU1198

Functional Information from PROSITE/UniProt

site_id	PS01232
Number of Residues	16
Details	PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL

Chain	Residue	Details
A	SER1066-LEU1081

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)