2ODG

Complex of barrier-to-autointegration factor and LEM-domain of emerin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0000793	cellular_component	condensed chromosome
A	0003677	molecular_function	DNA binding
A	0003690	molecular_function	double-stranded DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006325	biological_process	chromatin organization
A	0006979	biological_process	response to oxidative stress
A	0007084	biological_process	mitotic nuclear membrane reassembly
A	0009615	biological_process	response to virus
A	0010836	biological_process	negative regulation of protein ADP-ribosylation
A	0015074	biological_process	DNA integration
A	0032480	biological_process	negative regulation of type I interferon production
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0045071	biological_process	negative regulation of viral genome replication
A	0045824	biological_process	negative regulation of innate immune response
A	0051276	biological_process	chromosome organization
A	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
B	0000785	cellular_component	chromatin
B	0000793	cellular_component	condensed chromosome
B	0003677	molecular_function	DNA binding
B	0003690	molecular_function	double-stranded DNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006325	biological_process	chromatin organization
B	0006979	biological_process	response to oxidative stress
B	0007084	biological_process	mitotic nuclear membrane reassembly
B	0009615	biological_process	response to virus
B	0010836	biological_process	negative regulation of protein ADP-ribosylation
B	0015074	biological_process	DNA integration
B	0032480	biological_process	negative regulation of type I interferon production
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0045071	biological_process	negative regulation of viral genome replication
B	0045824	biological_process	negative regulation of innate immune response
B	0051276	biological_process	chromosome organization
B	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
C	0005635	cellular_component	nuclear envelope

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	Domain: {"description":"HhH","evidences":[{"source":"PubMed","id":"10924106","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine; by VRK1 and VRK2","evidences":[{"source":"PubMed","id":"16495336","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by viral VacV B1 kinase, VRK1 and VRK2","evidences":[{"source":"PubMed","id":"16371512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16495336","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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