2OD1

Solution structure of the MYND domain from human AML1-ETO

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003714	molecular_function	transcription corepressor activity
A	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 901

Chain	Residue
A	CYS663
A	CYS666
A	CYS683
A	CYS687

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 902

Chain	Residue
A	CYS674
A	CYS677
A	HIS695
A	CYS699

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Functional Information from PROSITE/UniProt

site_id	PS01360
Number of Residues	37
Details	ZF_MYND_1 Zinc finger MYND-type signature. Cwn..Cgrkaset..........CsgCntarYCgsfCqhkdwek..Hhhi.C

Chain	Residue	Details
A	CYS663-CYS699

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Zinc finger: {"description":"MYND-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00134","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00134","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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