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2OCT

Stefin B (Cystatin B) tetramer

Functional Information from GO Data
ChainGOidnamespacecontents
A0002020molecular_functionprotease binding
A0003723molecular_functionRNA binding
A0004866molecular_functionendopeptidase inhibitor activity
A0004869molecular_functioncysteine-type endopeptidase inhibitor activity
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005730cellular_componentnucleolus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0008344biological_processadult locomotory behavior
A0010466biological_processnegative regulation of peptidase activity
A0034774cellular_componentsecretory granule lumen
A0045861biological_processnegative regulation of proteolysis
A0062023cellular_componentcollagen-containing extracellular matrix
A0070062cellular_componentextracellular exosome
A1904724cellular_componenttertiary granule lumen
A1904813cellular_componentficolin-1-rich granule lumen
B0002020molecular_functionprotease binding
B0003723molecular_functionRNA binding
B0004866molecular_functionendopeptidase inhibitor activity
B0004869molecular_functioncysteine-type endopeptidase inhibitor activity
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005730cellular_componentnucleolus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0008344biological_processadult locomotory behavior
B0010466biological_processnegative regulation of peptidase activity
B0034774cellular_componentsecretory granule lumen
B0045861biological_processnegative regulation of proteolysis
B0062023cellular_componentcollagen-containing extracellular matrix
B0070062cellular_componentextracellular exosome
B1904724cellular_componenttertiary granule lumen
B1904813cellular_componentficolin-1-rich granule lumen
Functional Information from PROSITE/UniProt
site_idPS00287
Number of Residues14
DetailsCYSTATIN Cysteine proteases inhibitors signature. SQVVAGTNYfIKVH
ChainResidueDetails
ASER45-HIS58

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Reactive site
ChainResidueDetails
AGLY4
BGLY4

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylmethionine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895
ChainResidueDetails
AMET1
BMET1

222036

PDB entries from 2024-07-03

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