2OA1
Crystal Structure of RebH, a FAD-dependent halogenase from Lechevalieria aerocolonigenes, the L-Tryptophan with FAD complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 2001 |
| Chain | Residue |
| A | PRO355 |
| A | THR359 |
| A | GLY360 |
| A | FAD2004 |
| A | HOH2120 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TRP A 2002 |
| Chain | Residue |
| A | PHE111 |
| A | GLU357 |
| A | TYR454 |
| A | TYR455 |
| A | GLU461 |
| A | PHE465 |
| A | TRP466 |
| A | ASN470 |
| A | HOH2124 |
| A | HOH2139 |
| A | ILE52 |
| A | PRO53 |
| A | ILE82 |
| A | HIS109 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TRP A 2003 |
| Chain | Residue |
| A | HOH2037 |
| A | HOH2071 |
| B | ILE52 |
| B | PRO53 |
| B | ILE82 |
| B | HIS109 |
| B | SER110 |
| B | PHE111 |
| B | GLU357 |
| B | TYR454 |
| B | TYR455 |
| B | GLU461 |
| B | PHE465 |
| B | TRP466 |
| site_id | AC4 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE FAD A 2004 |
| Chain | Residue |
| A | GLY12 |
| A | GLY13 |
| A | THR15 |
| A | ALA16 |
| A | GLN38 |
| A | ALA39 |
| A | ASP41 |
| A | GLU49 |
| A | ALA50 |
| A | ASP195 |
| A | ARG196 |
| A | VAL197 |
| A | CYS227 |
| A | SER228 |
| A | GLY229 |
| A | ILE286 |
| A | PHE330 |
| A | THR348 |
| A | PHE352 |
| A | PRO355 |
| A | GLY360 |
| A | ILE361 |
| A | CL2001 |
| A | HOH2016 |
| A | HOH2036 |
| A | HOH2082 |
| A | HOH2089 |
| A | HOH2103 |
| A | HOH2116 |
| A | HOH2258 |
| A | HOH2358 |
| A | HOH2481 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADN B 2005 |
| Chain | Residue |
| B | GLY12 |
| B | GLY13 |
| B | ALA39 |
| B | ASP41 |
| B | ASP195 |
| B | ARG196 |
| B | VAL197 |
| B | CYS227 |
| B | SER228 |
| B | ARG231 |
| B | LEU233 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17876823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OA1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OAL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OAL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17876823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2E4G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OA1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17876823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OA1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"UniProtKB","id":"P95480","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
