2O90

Atomic resolution crystal structure of E.coli dihydroneopterin aldolase in complex with neopterin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004150	molecular_function	dihydroneopterin aldolase activity
A	0005737	cellular_component	cytoplasm
A	0006760	biological_process	folic acid-containing compound metabolic process
A	0016829	molecular_function	lyase activity
A	0016853	molecular_function	isomerase activity
A	0042802	molecular_function	identical protein binding
A	0046654	biological_process	tetrahydrofolate biosynthetic process
A	0046656	biological_process	folic acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE NEU A 131

Chain	Residue
A	GLY16
A	VAL72
A	GLU73
A	LYS98
A	ALA101
A	HOH145
A	HOH195
A	HOH258
A	HOH320
A	HOH334
A	VAL17
A	TYR18
A	GLU21
A	CYS50
A	LEU51
A	SER52
A	TYR53
A	LEU71

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:P56740, ECO:0000305|PubMed:25264482

Chain	Residue	Details
A	LYS98

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:25264482, ECO:0007744|PDB:2O90

Chain	Residue	Details
A	GLU21
A	TYR53
A	VAL72

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 2dhn

Chain	Residue	Details
A	LYS98
A	GLU21

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