2O8V
PAPS reductase in a covalent complex with thioredoxin C35A
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004604 | molecular_function | phosphoadenylyl-sulfate reductase (thioredoxin) activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006790 | biological_process | sulfur compound metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
A | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0015035 | molecular_function | protein-disulfide reductase activity |
B | 0015036 | molecular_function | disulfide oxidoreductase activity |
B | 0030337 | molecular_function | DNA polymerase processivity factor activity |
B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Nucleophile |
Chain | Residue | Details |
B | CYS32 | |
B | ALA35 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | SITE: Deprotonates C-terminal active site Cys |
Chain | Residue | Details |
B | ASP26 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Contributes to redox potential value |
Chain | Residue | Details |
B | GLY33 | |
B | PRO34 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842 |
Chain | Residue | Details |
B | LYS69 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1cqg |
Chain | Residue | Details |
B | ALA35 | |
B | CYS32 |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 279 |
Chain | Residue | Details |
A | ASP206 | electrostatic stabiliser, hydrogen bond donor |
A | LEU210 | electrostatic stabiliser, hydrogen bond donor |
A | GLY240 | activator, covalently attached, electrofuge, electrophile, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, polar interaction, proton acceptor, proton donor |