2O7V

Carboxylesterase AeCXE1 from Actinidia eriantha covalently inhibited by paraoxon

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
A	0106435	molecular_function	carboxylesterase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DEP A 401

Chain	Residue
A	GLY92
A	GLY93
A	SER169
A	ALA170
A	TRP231
A	MET278
A	HIS306

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Functional Information from PROSITE/UniProt

site_id	PS01173
Number of Residues	17
Details	LIPASE_GDXG_HIS Lipolytic enzymes "G-D-X-G" family, putative histidine active site. VVyFHGGGFilfSaaST

Chain	Residue	Details
A	VAL86-THR102

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000305

Chain	Residue	Details
A	SER169
A	ASP276
A	HIS306

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000305|PubMed:17256879, ECO:0007744|PDB:2O7V

Chain	Residue	Details
A	GLY92
A	ALA170

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: covalent => ECO:0000305|PubMed:17256879, ECO:0007744|PDB:2O7V

Chain	Residue	Details
A	SER169

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1jkm

Chain	Residue	Details
A	HIS306
A	ASP276
A	SER169

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