2O74

Structure of OHCU decarboxylase in complex with guanine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000255	biological_process	allantoin metabolic process
A	0005777	cellular_component	peroxisome
A	0006144	biological_process	purine nucleobase metabolic process
A	0016831	molecular_function	carboxy-lyase activity
A	0019628	biological_process	urate catabolic process
A	0051997	molecular_function	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
B	0000255	biological_process	allantoin metabolic process
B	0005777	cellular_component	peroxisome
B	0006144	biological_process	purine nucleobase metabolic process
B	0016831	molecular_function	carboxy-lyase activity
B	0019628	biological_process	urate catabolic process
B	0051997	molecular_function	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
C	0000255	biological_process	allantoin metabolic process
C	0005777	cellular_component	peroxisome
C	0006144	biological_process	purine nucleobase metabolic process
C	0016831	molecular_function	carboxy-lyase activity
C	0019628	biological_process	urate catabolic process
C	0051997	molecular_function	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
D	0000255	biological_process	allantoin metabolic process
D	0005777	cellular_component	peroxisome
D	0006144	biological_process	purine nucleobase metabolic process
D	0016831	molecular_function	carboxy-lyase activity
D	0019628	biological_process	urate catabolic process
D	0051997	molecular_function	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
E	0000255	biological_process	allantoin metabolic process
E	0005777	cellular_component	peroxisome
E	0006144	biological_process	purine nucleobase metabolic process
E	0016831	molecular_function	carboxy-lyase activity
E	0019628	biological_process	urate catabolic process
E	0051997	molecular_function	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
F	0000255	biological_process	allantoin metabolic process
F	0005777	cellular_component	peroxisome
F	0006144	biological_process	purine nucleobase metabolic process
F	0016831	molecular_function	carboxy-lyase activity
F	0019628	biological_process	urate catabolic process
F	0051997	molecular_function	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GUN A 1001

Chain	Residue
A	PRO68
A	ILE157
A	HOH1009
A	LEU70
A	SER84
A	GLU87
A	GLN88
A	PHE119
A	VAL120
A	ILE121
A	ALA123

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GUN B 2001

Chain	Residue
B	PRO68
B	LEU70
B	SER84
B	GLU87
B	GLN88
B	PHE119
B	VAL120
B	ILE121
B	ALA123
B	ILE157
B	HOH2103

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GUN C 3001

Chain	Residue
C	PRO68
C	LEU70
C	SER84
C	GLU87
C	GLN88
C	PHE119
C	VAL120
C	ILE121
C	ALA123
C	ILE157

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GUN D 4001

Chain	Residue
D	PRO68
D	LEU70
D	SER84
D	GLU87
D	GLN88
D	PHE119
D	VAL120
D	ILE121
D	ALA123
D	ILE157
D	HOH4045

---

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GUN F 5001

Chain	Residue
F	PRO68
F	LEU70
F	SER84
F	GLU87
F	GLN88
F	PHE119
F	ILE121
F	ALA123
F	ILE157

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GUN E 6001

Chain	Residue
E	PRO68
E	LEU70
E	SER84
E	GLU87
E	GLN88
E	PHE119
E	VAL120
E	ILE121
E	ALA123
E	ILE157
E	HOH6075

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	HIS67
B	HIS67
C	HIS67
D	HIS67
E	HIS67
F	HIS67

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	BINDING:

Chain	Residue	Details
A	PRO68
D	PRO68
D	SER84
D	PHE119
E	PRO68
E	SER84
E	PHE119
F	PRO68
F	SER84
F	PHE119
A	SER84
A	PHE119
B	PRO68
B	SER84
B	PHE119
C	PRO68
C	SER84
C	PHE119

---