2O3J
Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002009 | biological_process | morphogenesis of an epithelium |
| A | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| A | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| A | 0009792 | biological_process | embryo development ending in birth or egg hatching |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0018991 | biological_process | egg-laying behavior |
| A | 0040025 | biological_process | vulval development |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0002009 | biological_process | morphogenesis of an epithelium |
| B | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| B | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| B | 0009792 | biological_process | embryo development ending in birth or egg hatching |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0018991 | biological_process | egg-laying behavior |
| B | 0040025 | biological_process | vulval development |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0051287 | molecular_function | NAD binding |
| C | 0002009 | biological_process | morphogenesis of an epithelium |
| C | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| C | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| C | 0009792 | biological_process | embryo development ending in birth or egg hatching |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0018991 | biological_process | egg-laying behavior |
| C | 0040025 | biological_process | vulval development |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 901 |
| Chain | Residue |
| C | GLU427 |
| C | TYR430 |
| C | LEU450 |
| C | ASP451 |
| C | ALA454 |
| C | ILE458 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 902 |
| Chain | Residue |
| B | GLU427 |
| B | LEU450 |
| B | ASP451 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 903 |
| Chain | Residue |
| A | ALA85 |
| A | ALA87 |
| A | ASP88 |
| A | GLY127 |
| A | PRO128 |
| A | LYS129 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 904 |
| Chain | Residue |
| A | GLU427 |
| A | TYR430 |
| A | LEU450 |
| A | ASP451 |
| A | ILE458 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 905 |
| Chain | Residue |
| A | GLU190 |
| A | SER191 |
| A | ASN219 |
| A | THR220 |
| A | TRP221 |
| A | HOH949 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 906 |
| Chain | Residue |
| B | GLU190 |
| B | SER191 |
| B | ASN219 |
| B | THR220 |
| B | TRP221 |
| B | HOH1084 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 907 |
| Chain | Residue |
| C | SER191 |
| C | ASN219 |
| C | THR220 |
| C | TRP221 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 908 |
| Chain | Residue |
| B | LEU170 |
| B | ASN231 |
| B | ARG267 |
| B | HOH963 |
| B | HOH1225 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 909 |
| Chain | Residue |
| A | ARG267 |
| C | LEU170 |
| C | LYS227 |
| C | ASN231 |
| C | PHE284 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"O60701","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 99 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O60701","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| A | THR136 | |
| A | GLU172 | |
| A | ASN231 | |
| A | ASP287 | |
| A | CYS283 | |
| A | LYS227 |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| B | THR136 | |
| B | GLU172 | |
| B | ASN231 | |
| B | ASP287 | |
| B | CYS283 | |
| B | LYS227 |
| site_id | CSA3 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| C | THR136 | |
| C | GLU172 | |
| C | ASN231 | |
| C | ASP287 | |
| C | CYS283 | |
| C | LYS227 |
