2O0E
Mycobacterium tuberculosis epsp synthase in complex with S3P and PEP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | ARG68 |
| A | GLY142 |
| A | THR143 |
| A | GLY144 |
| A | HOH575 |
| A | HOH655 |
| A | HOH658 |
| A | HOH752 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 504 |
| Chain | Residue |
| A | HIS286 |
| A | ARG379 |
| A | HOH543 |
| A | HOH647 |
| A | HOH704 |
| A | HOH784 |
| A | HOH825 |
| A | HOH844 |
| A | HOH928 |
| A | HOH956 |
| A | ARG278 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 505 |
| Chain | Residue |
| A | LYS23 |
| A | LEU94 |
| A | ALA95 |
| A | GLY96 |
| A | THR97 |
| A | ARG124 |
| A | GLN169 |
| A | GLU341 |
| A | LYS410 |
| A | HOH599 |
| A | HOH1112 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE S3P A 501 |
| Chain | Residue |
| A | LYS23 |
| A | SER24 |
| A | ARG28 |
| A | THR97 |
| A | PHE101 |
| A | SER167 |
| A | SER168 |
| A | GLN169 |
| A | SER196 |
| A | HIS199 |
| A | GLU311 |
| A | HIS336 |
| A | HIS340 |
| A | HOH506 |
| A | HOH512 |
| A | HOH587 |
| A | HOH599 |
| A | HOH617 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PEP A 502 |
| Chain | Residue |
| A | LYS23 |
| A | LEU94 |
| A | GLY96 |
| A | ARG124 |
| A | GLN169 |
| A | GLU311 |
| A | GLU341 |
| A | ARG344 |
| A | HIS384 |
| A | ARG385 |
| A | LYS410 |
| A | HOH599 |
| A | HOH1111 |
| A | HOH1112 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"NOV-2006","submissionDatabase":"PDB data bank","title":"Complex of 3-phosphoshikimate 1-carboxyvinyltransferase.","authors":["Kachalova G.S.","Burenkov G.P.","Strizhov N.I.","Brunning M.G.","Bartunik H.D."]}},{"source":"PDB","id":"2O0E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"NOV-2006","submissionDatabase":"PDB data bank","title":"Complex of 3-phosphoshikimate 1-carboxyvinyltransferase.","authors":["Kachalova G.S.","Burenkov G.P.","Strizhov N.I.","Brunning M.G.","Bartunik H.D."]}},{"source":"PDB","id":"2O0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2O0D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2O0E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
