2O03

Crystal structure of FurB from M. tuberculosis- a Zinc uptake regulator

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001217	molecular_function	DNA-binding transcription repressor activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008270	molecular_function	zinc ion binding
A	0010043	biological_process	response to zinc ion
A	0032993	cellular_component	protein-DNA complex
A	0042803	molecular_function	protein homodimerization activity
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding
A	1900376	biological_process	regulation of secondary metabolite biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	ASP62
A	CYS76
A	HIS81
A	HIS83

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 202

Chain	Residue
A	CYS86
A	CYS89
A	CYS126
A	CYS129

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 203

Chain	Residue
A	HIS82
A	GLU101
A	HIS118
A	HIS80

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:17213192

Chain	Residue	Details
A	ASP62
A	HIS118
A	CYS126
A	CYS129
A	CYS76
A	HIS80
A	HIS81
A	HIS82
A	HIS83
A	CYS86
A	CYS89
A	GLU101

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