2NXQ

Crystal structure of calcium binding protein 1 from Entamoeba histolytica: a novel arrangement of EF hand motifs

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001891	cellular_component	phagocytic cup
A	0003779	molecular_function	actin binding
A	0003785	molecular_function	actin monomer binding
A	0005509	molecular_function	calcium ion binding
A	0005737	cellular_component	cytoplasm
A	0006897	biological_process	endocytosis
A	0006909	biological_process	phagocytosis
A	0031143	cellular_component	pseudopodium
A	0032231	biological_process	regulation of actin filament bundle assembly
A	0042995	cellular_component	cell projection
A	0045859	biological_process	regulation of protein kinase activity
A	0046872	molecular_function	metal ion binding
A	0050766	biological_process	positive regulation of phagocytosis
A	0051015	molecular_function	actin filament binding
A	1905303	biological_process	positive regulation of macropinocytosis
B	0001891	cellular_component	phagocytic cup
B	0003779	molecular_function	actin binding
B	0003785	molecular_function	actin monomer binding
B	0005509	molecular_function	calcium ion binding
B	0005737	cellular_component	cytoplasm
B	0006897	biological_process	endocytosis
B	0006909	biological_process	phagocytosis
B	0031143	cellular_component	pseudopodium
B	0032231	biological_process	regulation of actin filament bundle assembly
B	0042995	cellular_component	cell projection
B	0045859	biological_process	regulation of protein kinase activity
B	0046872	molecular_function	metal ion binding
B	0050766	biological_process	positive regulation of phagocytosis
B	0051015	molecular_function	actin filament binding
B	1905303	biological_process	positive regulation of macropinocytosis

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 149

Chain	Residue
A	ASP10
A	ASN12
A	ASP14
A	ALA16
A	GLU21
A	HOH215

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 150

Chain	Residue
A	GLU52
A	GLU57
A	HOH216
A	ASP46
A	ASP48
A	ASN50

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT A 201

Chain	Residue
A	TYR62

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT A 203

Chain	Residue
A	LYS33

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 151

Chain	Residue
B	ASP10
B	ASN12
B	ASP14
B	ALA16
B	GLU21
B	HOH222

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 152

Chain	Residue
B	ASP46
B	ASP48
B	ASN50
B	GLU52
B	GLU57
B	HOH223

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT B 202

Chain	Residue
B	TYR62

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site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT B 205

Chain	Residue
B	VAL26

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Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DVNGDGAVSyeEV

Chain	Residue	Details
A	ASP10-VAL22
A	ASP46-PHE58
A	ASP85-VAL97
A	ASP117-PHE129

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11724551","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17554780","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20550906","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23782698","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22906057","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1JFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2M7M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LI6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ULG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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