2NSH

E. coli PurE H45Q mutant complexed with nitro-AIR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005829	cellular_component	cytosol
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006189	biological_process	'de novo' IMP biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0034023	molecular_function	5-(carboxyamino)imidazole ribonucleotide mutase activity
A	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NIA A 300

Chain	Residue
A	GLY15
A	GLY71
A	ALA73
A	ALA74
A	HIS75
A	LEU76
A	PRO111
A	HOH327
A	HOH346
A	SER16
A	SER18
A	ASP19
A	SER43
A	ALA44
A	GLN45
A	ARG46
A	ALA70

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01929, ECO:0000269|PubMed:10574791

Chain	Residue	Details
A	LYS17
A	TRP20
A	THR47

---