Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006304 | biological_process | DNA modification |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
| A | 0009307 | biological_process | DNA restriction-modification system |
| A | 0032259 | biological_process | methylation |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0006304 | biological_process | DNA modification |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
| D | 0009307 | biological_process | DNA restriction-modification system |
| D | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NEA A 601 |
| Chain | Residue |
| A | ARG20 |
| A | ASP89 |
| A | PHE90 |
| A | ASN105 |
| A | PRO107 |
| A | PHE146 |
| A | HOH724 |
| A | HOH788 |
| A | HOH850 |
| A | HOH907 |
| A | VAL21 |
| A | ALA47 |
| A | ALA49 |
| A | GLU71 |
| A | ILE72 |
| A | ASP73 |
| A | ALA76 |
| A | ALA88 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NEA D 602 |
| Chain | Residue |
| D | VAL21 |
| D | ALA47 |
| D | GLU71 |
| D | ILE72 |
| D | ALA88 |
| D | ASP89 |
| D | PHE90 |
| D | ASN105 |
| D | PRO107 |
| D | PHE146 |
| D | GOL701 |
| D | GOL702 |
| D | HOH786 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 701 |
| Chain | Residue |
| D | VAL121 |
| D | TYR129 |
| D | LEU142 |
| D | NEA602 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL D 702 |
| Chain | Residue |
| D | VAL21 |
| D | ASN105 |
| D | PRO106 |
| D | PRO107 |
| D | TYR108 |
| D | LYS199 |
| D | NEA602 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA A 703 |
| Chain | Residue |
| A | ILE242 |
| A | ARG244 |
| A | GLU246 |
| A | ARG402 |
| A | HOH869 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IPA E 704 |
| Chain | Residue |
| D | ARG296 |
| E | DG8 |
| F | DA14 |
| F | DT15 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA B 705 |
| Chain | Residue |
| A | ARG296 |
| B | DG8 |
| B | DT9 |
| C | DT15 |
| C | HOH26 |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. ILGNPPY |
| Chain | Residue | Details |
| A | ILE102-TYR108 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR23 | |
| D | PRO107 | |
| A | GLU45 | |
| A | GLU71 | |
| A | ASP89 | |
| A | PRO107 | |
| D | THR23 | |
| D | GLU45 | |
| D | GLU71 | |
| D | ASP89 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Important for catalytic activity => ECO:0007744|PDB:2ADM |
| Chain | Residue | Details |
| A | ASN105 | |
| A | TYR108 | |
| D | ASN105 | |
| D | TYR108 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Important for catalytic activity; via amide nitrogen => ECO:0007744|PDB:2ADM |
| Chain | Residue | Details |
| A | PRO106 | |
| D | PRO106 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 2adm |
| Chain | Residue | Details |
| A | PRO106 | |
| A | ASN105 | |
| A | TYR108 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 2adm |
| Chain | Residue | Details |
| D | PRO106 | |
| D | ASN105 | |
| D | TYR108 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 46 |
| Chain | Residue | Details |
| A | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| A | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| A | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| A | PHE196 | steric role |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 46 |
| Chain | Residue | Details |
| D | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| D | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| D | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| D | PHE196 | steric role |
