2NO5
Crystal Structure analysis of a Dehalogenase with intermediate complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0018784 | molecular_function | (S)-2-haloacid dehalogenase activity |
| A | 0019120 | molecular_function | hydrolase activity, acting on acid halide bonds, in C-halide compounds |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0018784 | molecular_function | (S)-2-haloacid dehalogenase activity |
| B | 0019120 | molecular_function | hydrolase activity, acting on acid halide bonds, in C-halide compounds |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Region: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"17368477","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"17368477","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2NO5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17368477","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2NO5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"17368477","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lvh |
| Chain | Residue | Details |
| A | LYS152 | |
| A | SER119 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lvh |
| Chain | Residue | Details |
| B | LYS152 | |
| B | SER119 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1lvh |
| Chain | Residue | Details |
| A | ASP181 | |
| A | ARG42 | |
| A | SER119 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1lvh |
| Chain | Residue | Details |
| B | ASP181 | |
| B | ARG42 | |
| B | SER119 |
| site_id | CSA5 |
| Number of Residues | 8 |
| Details | Annotated By Reference To The Literature 1lvh |
| Chain | Residue | Details |
| A | ASP181 | |
| A | THR15 | |
| A | LYS152 | |
| A | ARG42 | |
| A | ASN120 | |
| A | TRP180 | |
| A | ASN178 | |
| A | SER176 |
| site_id | CSA6 |
| Number of Residues | 8 |
| Details | Annotated By Reference To The Literature 1lvh |
| Chain | Residue | Details |
| B | ASP181 | |
| B | THR15 | |
| B | LYS152 | |
| B | ARG42 | |
| B | ASN120 | |
| B | TRP180 | |
| B | ASN178 | |
| B | SER176 |
