2NNR
Crystal structure of chagasin, cysteine protease inhibitor from Trypanosoma cruzi
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004869 | molecular_function | cysteine-type endopeptidase inhibitor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0009986 | cellular_component | cell surface |
| A | 0020016 | cellular_component | ciliary pocket |
| A | 0030414 | molecular_function | peptidase inhibitor activity |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0004869 | molecular_function | cysteine-type endopeptidase inhibitor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0009986 | cellular_component | cell surface |
| B | 0020016 | cellular_component | ciliary pocket |
| B | 0030414 | molecular_function | peptidase inhibitor activity |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | ASN29 |
| B | HOH3094 |
| A | GLY68 |
| A | GOL3001 |
| A | GOL3002 |
| A | HOH3052 |
| A | HOH3074 |
| A | HOH3107 |
| B | ASN29 |
| B | HOH3010 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 2001 |
| Chain | Residue |
| B | PRO60 |
| B | ASP61 |
| B | SER62 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 3001 |
| Chain | Residue |
| A | SO41001 |
| B | LYS7 |
| B | PRO27 |
| B | TRP36 |
| B | TYR89 |
| B | GLU101 |
| B | HOH3017 |
| B | HOH3094 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 3002 |
| Chain | Residue |
| A | LYS7 |
| A | PRO27 |
| A | TRP36 |
| A | TYR89 |
| A | GLU101 |
| A | SO41001 |
| A | HOH3025 |
| A | HOH3107 |
| B | HOH3012 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 3003 |
| Chain | Residue |
| A | ARG91 |
| A | ARG91 |
| A | TRP93 |
| A | THR94 |
| A | GOL3004 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 3004 |
| Chain | Residue |
| A | ARG91 |
| A | TRP93 |
| A | GOL3003 |
| A | HOH3082 |
| B | THR31 |
| B | HOH3074 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 3005 |
| Chain | Residue |
| A | SER97 |
| A | HIS98 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 3006 |
| Chain | Residue |
| A | ASN55 |
| A | LYS56 |
| A | TYR57 |
| A | HOH3024 |
| A | HOH3041 |
| A | HOH3060 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 3007 |
| Chain | Residue |
| A | THR31 |
| A | GLY41 |
| A | PRO92 |
| A | HOH3034 |
| A | HOH3035 |
| B | ARG91 |
| B | HOH3078 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Motif: {"description":"BC loop","evidences":[{"source":"PubMed","id":"17502099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17561110","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18515357","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19143838","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Motif: {"description":"DE loop","evidences":[{"source":"PubMed","id":"17502099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17561110","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18515357","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19143838","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Motif: {"description":"FG loop","evidences":[{"source":"PubMed","id":"17502099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17561110","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18515357","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19143838","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
