2NN3

structure of pro-sf-caspase-1

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0004197	molecular_function	cysteine-type endopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0006508	biological_process	proteolysis
C	0006915	biological_process	apoptotic process
C	0008233	molecular_function	peptidase activity
C	0008234	molecular_function	cysteine-type peptidase activity
C	0016322	biological_process	neuron remodeling
C	0016787	molecular_function	hydrolase activity
C	0043525	biological_process	positive regulation of neuron apoptotic process
C	0045476	biological_process	nurse cell apoptotic process
C	0045751	biological_process	negative regulation of Toll signaling pathway
C	1990525	molecular_function	BIR domain binding
D	0004197	molecular_function	cysteine-type endopeptidase activity
D	0005737	cellular_component	cytoplasm
D	0006508	biological_process	proteolysis
D	0006915	biological_process	apoptotic process
D	0008233	molecular_function	peptidase activity
D	0008234	molecular_function	cysteine-type peptidase activity
D	0016322	biological_process	neuron remodeling
D	0016787	molecular_function	hydrolase activity
D	0043525	biological_process	positive regulation of neuron apoptotic process
D	0045476	biological_process	nurse cell apoptotic process
D	0045751	biological_process	negative regulation of Toll signaling pathway
D	1990525	molecular_function	BIR domain binding

Functional Information from PROSITE/UniProt

site_id	PS01122
Number of Residues	12
Details	CASPASE_CYS Caspase family cysteine active site. KPKLFFIQACQG

Chain	Residue	Details
C	LYS169-GLY180

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	10
Details	Propeptide: {"featureId":"PRO_0000004660","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1qx3

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1qx3