2NDF

Solution NMR structures of AF9 yeats domain in complex with histon H3 acetylation at K18

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0030527	molecular_function	structural constituent of chromatin

Functional Information from PROSITE/UniProt

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
B	LYS214-LEU220

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	137
Details	Domain: {"description":"YEATS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00376","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Region: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Citrulline; alternate","evidences":[{"source":"PubMed","id":"15345777","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16497732","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16567635","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"16267050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Lipidation: {"description":"N6-decanoyllysine","evidences":[{"source":"PubMed","id":"35939806","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---