2NA0

NMR structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) mutant V77E in a Ca2+-free/Mg2+-bound Activator State

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001750	cellular_component	photoreceptor outer segment
A	0001917	cellular_component	photoreceptor inner segment
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0007601	biological_process	visual perception
A	0007602	biological_process	phototransduction
A	0008048	molecular_function	calcium sensitive guanylate cyclase activator activity
A	0016020	cellular_component	membrane
A	0030249	molecular_function	guanylate cyclase regulator activity
A	0031282	biological_process	regulation of guanylate cyclase activity
A	0031284	biological_process	positive regulation of guanylate cyclase activity
A	0042995	cellular_component	cell projection
A	0046872	molecular_function	metal ion binding
A	0071277	biological_process	cellular response to calcium ion
A	0120199	cellular_component	cone photoreceptor outer segment

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DFNKDGYIDfmEY

Chain	Residue	Details
A	ASP64-TYR76
A	ASP100-LEU112
A	ASP144-PHE156

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:26703466

Chain	Residue	Details
A	ASP64
A	GLU111
A	ASP144
A	ASN146
A	ASP148
A	GLU150
A	GLU155
A	ASN66
A	ASP68
A	TYR70
A	GLU75
A	ASP100
A	ASP102
A	ASN104
A	CYS106

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Deamidated asparagine => ECO:0000255

Chain	Residue	Details
A	ASN3

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site_id	SWS_FT_FI3
Number of Residues	1
Details	LIPID: N-myristoyl glycine => ECO:0000269|PubMed:7520254

Chain	Residue	Details
A	GLY2

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