2N5B

Structures of the OXIDIZED state of the mutant D24A of yeast thioredoxin 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000011	biological_process	vacuole inheritance
A	0000139	cellular_component	Golgi membrane
A	0000324	cellular_component	fungal-type vacuole
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
A	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A	0009263	biological_process	deoxyribonucleotide biosynthetic process
A	0015031	biological_process	protein transport
A	0015035	molecular_function	protein-disulfide reductase activity
A	0015036	molecular_function	disulfide oxidoreductase activity
A	0016020	cellular_component	membrane
A	0042144	biological_process	vacuole fusion, non-autophagic
A	0045454	biological_process	cell redox homeostasis
A	0120124	cellular_component	membrane fusion priming complex

Functional Information from PROSITE/UniProt

site_id	PS00194
Number of Residues	19
Details	THIOREDOXIN_1 Thioredoxin family active site. VVaFYatWCGPCKmIapmI

Chain	Residue	Details
A	VAL22-ILE40

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Deprotonates C-terminal active site Cys

Chain	Residue	Details
A	ALA24

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Contributes to redox potential value

site_id	SWS_FT_FI4
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744\|PubMed:22106047