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2N2A

Spatial structure of HER2/ErbB2 dimeric transmembrane domain in the presence of cytoplasmic juxtamembrane domains

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues44
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues26
DetailsRegion: {"description":"Required for interaction with KPNB1 and EEA1","evidences":[{"source":"PubMed","id":"16314522","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues26
DetailsMotif: {"description":"Nuclear localization signal"}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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