2N28

Solid-state NMR structure of Vpu

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005261	molecular_function	monoatomic cation channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0019076	biological_process	viral release from host cell
A	0032801	biological_process	receptor catabolic process
A	0033644	cellular_component	host cell membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039587	biological_process	symbiont-mediated-mediated suppression of host tetherin activity
A	0042609	molecular_function	CD4 receptor binding
A	0052031	biological_process	symbiont-mediated perturbation of host defense response
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
A	0098655	biological_process	monoatomic cation transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"HAMAP-Rule","id":"MF_04082","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_04082","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	53
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"HAMAP-Rule","id":"MF_04082","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by host CK2","evidences":[{"source":"HAMAP-Rule","id":"MF_04082","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---