2N28

Solid-state NMR structure of Vpu

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005261	molecular_function	monoatomic cation channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0019076	biological_process	viral release from host cell
A	0032801	biological_process	receptor catabolic process
A	0033644	cellular_component	host cell membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039503	biological_process	obsolete suppression by virus of host innate immune response
A	0039587	biological_process	suppression by virus of host tetherin activity
A	0042609	molecular_function	CD4 receptor binding
A	0098655	biological_process	monoatomic cation transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	TOPO_DOM: Extracellular => ECO:0000255|HAMAP-Rule:MF_04082

Chain	Residue	Details
A	MET1-ILE6

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site_id	SWS_FT_FI2
Number of Residues	20
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_04082

Chain	Residue	Details
A	ALA7-ILE27

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site_id	SWS_FT_FI3
Number of Residues	53
Details	TOPO_DOM: Cytoplasmic => ECO:0000255|HAMAP-Rule:MF_04082

Chain	Residue	Details
A	GLU28-LEU81

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine; by host CK2 => ECO:0000255|HAMAP-Rule:MF_04082

Chain	Residue	Details
A	SER52
A	SER56

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