Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2MZH

NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) in Complex with Zwitterionic Membrane

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004175	molecular_function	endopeptidase activity
A	0004222	molecular_function	metalloendopeptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006508	biological_process	proteolysis
A	0006509	biological_process	membrane protein ectodomain proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0022617	biological_process	extracellular matrix disassembly
A	0030198	biological_process	extracellular matrix organization
A	0030335	biological_process	positive regulation of cell migration
A	0030574	biological_process	collagen catabolic process
A	0031012	cellular_component	extracellular matrix
A	0031293	biological_process	membrane protein intracellular domain proteolysis
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 301

Chain	Residue
A	ASP133
A	GLY165
A	GLY167
A	ASP169

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 302

Chain	Residue
A	GLU176
A	ASP150
A	GLY151
A	GLY153
A	THR155
A	ASP173

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 303

Chain	Residue
A	HIS143
A	ASP145
A	HIS158
A	HIS171

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 304

Chain	Residue
A	ASP71
A	HIS194
A	HIS198
A	HIS204

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 305

Chain	Residue
A	PX4321
A	PX4322
A	PX4328
A	PX4362

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 306

Chain	Residue
A	PX4313
A	PX4314
A	PX4354
A	PX4364
A	PX4403

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 307

Chain	Residue
A	PX4310
A	PX4311
A	PX4348
A	PX4363
A	PX4403

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 308

Chain	Residue
A	PX4315
A	PX4319
A	PX4340
A	PX4375

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 309

Chain	Residue
A	PX4357
A	PX4358
A	PX4366

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 310

Chain	Residue
A	PX4307
A	PX4311
A	PX4359
A	PX4363

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 311

Chain	Residue
A	PX4307
A	PX4310
A	PX4363
A	PX4364
A	PX4414

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 312

Chain	Residue
A	PX4315
A	PX4317
A	PX4319
A	PX4327
A	PX4341

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 313

Chain	Residue
A	PX4306
A	PX4348
A	PX4354
A	PX4356
A	PX4364

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 314

Chain	Residue
A	PX4306
A	PX4345
A	PX4364

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 315

Chain	Residue
A	PX4308
A	PX4312
A	PX4319
A	PX4322
A	PX4373

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 316

Chain	Residue
A	PX4317
A	PX4318
A	PX4324
A	PX4325
A	PX4341
A	PX4350

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 317

Chain	Residue
A	PX4312
A	PX4316
A	PX4318
A	PX4319

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 318

Chain	Residue
A	PX4316
A	PX4317
A	PX4322
A	PX4323
A	PX4340
A	PX4375

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 319

Chain	Residue
A	PX4308
A	PX4312
A	PX4315
A	PX4317
A	PX4327

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 320

Chain	Residue
A	PX4328
A	PX4335
A	PX4353
A	PX4400

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 321

Chain	Residue
A	PX4305
A	PX4328
A	PX4330
A	PX4331
A	PX4335
A	PX4377
A	PX4378

site_id	CC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 322

Chain	Residue
A	PX4315
A	PX4318
A	PX4332
A	PX4361
A	PX4372
A	PX4373
A	PX4305

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 323

Chain	Residue
A	PX4318
A	PX4324
A	PX4340
A	PX4375

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PX4 A 324

Chain	Residue
A	ASP99
A	PX4316
A	PX4323
A	PX4325
A	PX4333
A	PX4339
A	PX4382
A	PX4398

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 325

Chain	Residue
A	PX4316
A	PX4324
A	PX4333
A	PX4349
A	PX4403

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 326

Chain	Residue
A	PX4343
A	PX4353
A	PX4360

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 327

Chain	Residue
A	PX4312
A	PX4319

site_id	DC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 328

Chain	Residue
A	PX4305
A	PX4320
A	PX4321
A	PX4335
A	PX4342
A	PX4362

site_id	DC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 329

Chain	Residue
A	PX4336
A	PX4338
A	PX4344
A	PX4346
A	PX4347
A	PX4351
A	PX4366

site_id	DC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PX4 A 330

Chain	Residue
A	ARG98
A	ARG140
A	ASP175
A	PX4321
A	PX4331
A	PX4332
A	PX4335
A	PX4339

site_id	DC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PX4 A 331

Chain	Residue
A	ARG98
A	ARG140
A	PX4321
A	PX4330
A	PX4332
A	PX4338
A	PX4339
A	PX4340
A	PX4347
A	PX4355

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 332

Chain	Residue
A	PX4322
A	PX4330
A	PX4331
A	PX4340

site_id	DC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 333

Chain	Residue
A	PX4324
A	PX4325
A	PX4347
A	PX4348
A	PX4355
A	PX4356

site_id	DC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 334

Chain	Residue
A	PX4335
A	PX4342
A	PX4343
A	PX4351
A	PX4400

site_id	DC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 335

Chain	Residue
A	PX4320
A	PX4321
A	PX4328
A	PX4330
A	PX4334
A	PX4342

site_id	DC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 336

Chain	Residue
A	PX4329
A	PX4351
A	PX4358

site_id	EC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 337

Chain	Residue
A	PX4344
A	PX4346
A	PX4402

site_id	EC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 338

Chain	Residue
A	PX4329
A	PX4331
A	PX4342
A	PX4346
A	PX4347
A	PX4351

site_id	EC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 339

Chain	Residue
A	ARG98
A	PX4324
A	PX4330
A	PX4331
A	PX4355
A	PX4381

site_id	EC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 340

Chain	Residue
A	PX4308
A	PX4318
A	PX4323
A	PX4331
A	PX4332
A	PX4355

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 341

Chain	Residue
A	PX4312
A	PX4316
A	PX4350

site_id	EC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 342

Chain	Residue
A	PX4328
A	PX4334
A	PX4335
A	PX4338
A	PX4351
A	PX4366

site_id	EC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 343

Chain	Residue
A	PX4326
A	PX4334

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 344

Chain	Residue
A	PX4329
A	PX4337
A	PX4345
A	PX4401

site_id	EC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 345

Chain	Residue
A	PX4314
A	PX4344
A	PX4352
A	PX4354
A	PX4365

site_id	FC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 346

Chain	Residue
A	PX4329
A	PX4337
A	PX4338
A	PX4347
A	PX4355
A	PX4393

site_id	FC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PX4 A 347

Chain	Residue
A	VAL94
A	PX4329
A	PX4331
A	PX4333
A	PX4338
A	PX4346
A	PX4355
A	PX4387

site_id	FC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 348

Chain	Residue
A	PX4307
A	PX4313
A	PX4333
A	PX4349
A	PX4356

site_id	FC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 349

Chain	Residue
A	PX4325
A	PX4348
A	PX4350
A	PX4363

site_id	FC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 350

Chain	Residue
A	PX4316
A	PX4341
A	PX4349

site_id	FC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 351

Chain	Residue
A	PX4329
A	PX4334
A	PX4336
A	PX4338
A	PX4342
A	PX4358

site_id	FC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 352

Chain	Residue
A	PX4345
A	PX4365
A	PX4417

site_id	FC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 353

Chain	Residue
A	PX4320
A	PX4326
A	PX4360

site_id	FC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 354

Chain	Residue
A	TRP129
A	PX4306
A	PX4313
A	PX4345

site_id	GC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PX4 A 355

Chain	Residue
A	TYR96
A	ARG98
A	PX4331
A	PX4333
A	PX4339
A	PX4340
A	PX4346
A	PX4347
A	PX4356

site_id	GC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 356

Chain	Residue
A	TYR96
A	PX4313
A	PX4333
A	PX4348
A	PX4355
A	PX4418

site_id	GC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 357

Chain	Residue
A	PX4309
A	PX4358
A	PX4406

site_id	GC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 358

Chain	Residue
A	PX4309
A	PX4336
A	PX4351
A	PX4357
A	PX4392

site_id	GC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 359

Chain	Residue
A	PX4310

site_id	GC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 360

Chain	Residue
A	PX4326
A	PX4353
A	PX4367

site_id	GC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 361

Chain	Residue
A	PX4322
A	PX4362

site_id	GC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 362

Chain	Residue
A	PX4305
A	PX4328
A	PX4361

site_id	GC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 363

Chain	Residue
A	PX4307
A	PX4310
A	PX4311
A	PX4349

site_id	HC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 364

Chain	Residue
A	PX4306
A	PX4311
A	PX4313
A	PX4314

site_id	HC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 365

Chain	Residue
A	PX4345
A	PX4352
A	PX4379

site_id	HC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 366

Chain	Residue
A	PX4309
A	PX4329
A	PX4342
A	PX4409

site_id	HC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 367

Chain	Residue
A	PX4360

site_id	HC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 368

Chain	Residue
A	PX4424
A	PX4429
A	PX4430

site_id	HC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 369

Chain	Residue
A	PX4370
A	PX4377
A	PX4391
A	PX4419
A	PX4425

site_id	HC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 370

Chain	Residue
A	PX4369
A	PX4419
A	PX4425

site_id	HC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 371

Chain	Residue
A	PX4386
A	PX4388
A	PX4394
A	PX4404
A	PX4412
A	PX4418

site_id	HC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 372

Chain	Residue
A	PX4322
A	PX4373
A	PX4421
A	PX4428

site_id	IC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 373

Chain	Residue
A	PX4315
A	PX4322
A	PX4372
A	PX4375
A	PX4381
A	PX4421

site_id	IC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 374

Chain	Residue
A	PX4375
A	PX4382
A	PX4398
A	PX4429

site_id	IC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PX4 A 375

Chain	Residue
A	PX4308
A	PX4318
A	PX4323
A	PX4373
A	PX4374
A	PX4380
A	PX4382
A	PX4421
A	PX4429

site_id	IC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 376

Chain	Residue
A	PX4383
A	PX4390
A	PX4397
A	PX4398
A	PX4429
A	PX4430

site_id	IC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 377

Chain	Residue
A	PX4321
A	PX4369
A	PX4378
A	PX4387
A	PX4391

site_id	IC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 378

Chain	Residue
A	PX4321
A	PX4377
A	PX4381
A	PX4385
A	PX4387

site_id	IC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 379

Chain	Residue
A	PX4365
A	PX4418
A	PX4420
A	PX4427

site_id	IC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 380

Chain	Residue
A	PX4375
A	PX4381
A	PX4411

site_id	IC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 381

Chain	Residue
A	PX4339
A	PX4373
A	PX4378
A	PX4380
A	PX4385
A	PX4411

site_id	JC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 382

Chain	Residue
A	PX4324
A	PX4374
A	PX4375
A	PX4385
A	PX4387
A	PX4398

site_id	JC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 383

Chain	Residue
A	PX4376
A	PX4388
A	PX4397
A	PX4413
A	PX4429

site_id	JC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 384

Chain	Residue
A	PX4386
A	PX4393
A	PX4395
A	PX4400
A	PX4408

site_id	JC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 385

Chain	Residue
A	PX4378
A	PX4381
A	PX4382
A	PX4387

site_id	JC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 386

Chain	Residue
A	PX4371
A	PX4384
A	PX4387
A	PX4391
A	PX4394
A	PX4395
A	PX4400

site_id	JC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 387

Chain	Residue
A	PX4347
A	PX4377
A	PX4378
A	PX4382
A	PX4385
A	PX4386

site_id	JC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 388

Chain	Residue
A	PX4371
A	PX4383
A	PX4389
A	PX4394
A	PX4395

site_id	JC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 389

Chain	Residue
A	PX4388
A	PX4394
A	PX4395
A	PX4397
A	PX4398
A	PX4403
A	PX4412

site_id	JC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 390

Chain	Residue
A	PX4376
A	PX4415
A	PX4430

site_id	KC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 391

Chain	Residue
A	PX4369
A	PX4377
A	PX4386
A	PX4400
A	PX4425

site_id	KC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 392

Chain	Residue
A	PX4358
A	PX4393
A	PX4394
A	PX4402
A	PX4408

site_id	KC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PX4 A 393

Chain	Residue
A	PX4346
A	PX4384
A	PX4392
A	PX4394
A	PX4400
A	PX4402
A	PX4408
A	PX4409

site_id	KC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PX4 A 394

Chain	Residue
A	PX4371
A	PX4386
A	PX4388
A	PX4389
A	PX4392
A	PX4393
A	PX4395
A	PX4404
A	PX4418

site_id	KC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 395

Chain	Residue
A	PX4384
A	PX4386
A	PX4388
A	PX4389
A	PX4394
A	PX4398

site_id	KC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 396

Chain	Residue
A	PX4405
A	PX4414
A	PX4422

site_id	KC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 397

Chain	Residue
A	PX4376
A	PX4383
A	PX4389
A	PX4403
A	PX4415

site_id	KC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 398

Chain	Residue
A	PX4324
A	PX4374
A	PX4376
A	PX4382
A	PX4389
A	PX4395
A	PX4403

site_id	KC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 399

Chain	Residue
A	PX4400
A	PX4408

site_id	LC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PX4 A 400

Chain	Residue
A	PX4320
A	PX4334
A	PX4384
A	PX4386
A	PX4391
A	PX4393
A	PX4399
A	PX4425

site_id	LC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 401

Chain	Residue
A	PX4344
A	PX4402
A	PX4417
A	PX4427

site_id	LC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 402

Chain	Residue
A	PX4337
A	PX4392
A	PX4393
A	PX4401
A	PX4418
A	PX4427

site_id	LC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 403

Chain	Residue
A	PX4306
A	PX4307
A	PX4325
A	PX4389
A	PX4397
A	PX4398
A	PX4412

site_id	LC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 404

Chain	Residue
A	PX4371
A	PX4394
A	PX4405
A	PX4412
A	PX4414
A	PX4418
A	PX4420

site_id	LC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 405

Chain	Residue
A	PX4396
A	PX4404
A	PX4414
A	PX4420
A	PX4431

site_id	LC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 406

Chain	Residue
A	PX4357
A	PX4408
A	PX4409

site_id	LC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 407

Chain	Residue
A	PX4423

site_id	LC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 408

Chain	Residue
A	PX4384
A	PX4392
A	PX4393
A	PX4399
A	PX4406

site_id	MC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 409

Chain	Residue
A	PX4366
A	PX4393
A	PX4406
A	PX4417

site_id	MC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 411

Chain	Residue
A	PX4380
A	PX4381

site_id	MC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 412

Chain	Residue
A	PX4371
A	PX4389
A	PX4403
A	PX4404

site_id	MC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 413

Chain	Residue
A	PX4383
A	PX4421
A	PX4428
A	PX4429

site_id	MC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 414

Chain	Residue
A	PX4311
A	PX4396
A	PX4404
A	PX4405
A	PX4422

site_id	MC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 415

Chain	Residue
A	PX4390
A	PX4397

site_id	MC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 416

Chain	Residue
A	PX4422

site_id	MC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 417

Chain	Residue
A	PX4352
A	PX4401
A	PX4409

site_id	MC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PX4 A 418

Chain	Residue
A	PX4356
A	PX4371
A	PX4379
A	PX4394
A	PX4402
A	PX4404
A	PX4427

site_id	NC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 419

Chain	Residue
A	PX4369
A	PX4370
A	PX4426

site_id	NC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 420

Chain	Residue
A	PX4379
A	PX4404
A	PX4405

site_id	NC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PX4 A 421

Chain	Residue
A	PX4372
A	PX4373
A	PX4375
A	PX4413
A	PX4428

site_id	NC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 422

Chain	Residue
A	PX4396
A	PX4414
A	PX4416
A	PX4431

site_id	NC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 423

Chain	Residue
A	PX4407

site_id	NC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 424

Chain	Residue
A	PX4368
A	PX4430

site_id	NC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 425

Chain	Residue
A	PX4369
A	PX4370
A	PX4391
A	PX4400

site_id	NC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 A 426

Chain	Residue
A	PX4419

site_id	NC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 427

Chain	Residue
A	PX4379
A	PX4401
A	PX4402
A	PX4418

site_id	OC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 A 428

Chain	Residue
A	PX4372
A	PX4413
A	PX4421

site_id	OC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX4 A 429

Chain	Residue
A	PX4368
A	PX4374
A	PX4375
A	PX4376
A	PX4383
A	PX4413

site_id	OC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 430

Chain	Residue
A	PX4368
A	PX4376
A	PX4390
A	PX4424

site_id	OC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 A 431

Chain	Residue
A	PX4405
A	PX4422

Functional Information from PROSITE/UniProt

site_id	PS00546
Number of Residues	8
Details	CYSTEINE_SWITCH Matrixins cysteine switch. PRCGvPDV

Chain	Residue	Details
A	PRO65-VAL72

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Motif: {"description":"Cysteine switch","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"description":"in inhibited form","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	17
Details	Binding site: {}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)