2MYZ
The Solution Structure of the Magnesium-bound Conantokin-R1B Mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0035792 | cellular_component | host cell postsynaptic membrane |
Functional Information from PROSITE/UniProt
| site_id | PS60025 |
| Number of Residues | 14 |
| Details | CONANTOKIN Conantokin family signature. GEEElaENQ.EfARE |
| Chain | Residue | Details |
| A | GLY1-CGU14 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: via 4-carboxyglutamate => ECO:0000269|PubMed:26048991 |
| Chain | Residue | Details |
| A | CGU3 | |
| A | CGU7 | |
| A | PHE11 | |
| A | LEU15 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Important for selectivity => ECO:0000305|PubMed:22594498, ECO:0000305|PubMed:26048991, ECO:0000305|PubMed:27981829 |
| Chain | Residue | Details |
| A | ASN8 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Important for activity (Pro and hydroxyPro) => ECO:0000305|PubMed:22594498, ECO:0000305|PubMed:26048991, ECO:0000305|PubMed:27981829 |
| Chain | Residue | Details |
| A | CGU10 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | MOD_RES: 4-carboxyglutamate => ECO:0000250|UniProtKB:P07231, ECO:0000305|PubMed:22594498 |
| Chain | Residue | Details |
| A | CGU3 | |
| A | CGU4 | |
| A | CGU7 | |
| A | PHE11 | |
| A | LEU15 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: 4-hydroxyproline => ECO:0000305|PubMed:22594498 |
| Chain | Residue | Details |
| A | CGU10 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Asparagine amide => ECO:0000250|UniProtKB:P07231, ECO:0000305|PubMed:22594498 |
| Chain | Residue | Details |
| A | NH218 |
