2MXC

Solution structure of the full length sorting nexin 3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005768	cellular_component	endosome
A	0005769	cellular_component	early endosome
A	0005829	cellular_component	cytosol
A	0008289	molecular_function	lipid binding
A	0009617	biological_process	response to bacterium
A	0010008	cellular_component	endosome membrane
A	0010314	molecular_function	phosphatidylinositol-5-phosphate binding
A	0010324	biological_process	membrane invagination
A	0010976	biological_process	positive regulation of neuron projection development
A	0015031	biological_process	protein transport
A	0019903	molecular_function	protein phosphatase binding
A	0022615	biological_process	protein to membrane docking
A	0030111	biological_process	regulation of Wnt signaling pathway
A	0030136	cellular_component	clathrin-coated vesicle
A	0030904	cellular_component	retromer complex
A	0031901	cellular_component	early endosome membrane
A	0032009	cellular_component	early phagosome
A	0032266	molecular_function	phosphatidylinositol-3-phosphate binding
A	0032456	biological_process	endocytic recycling
A	0034499	biological_process	late endosome to Golgi transport
A	0035091	molecular_function	phosphatidylinositol binding
A	0042177	biological_process	negative regulation of protein catabolic process
A	0045335	cellular_component	phagocytic vesicle
A	0046597	biological_process	negative regulation of viral entry into host cell
A	0050765	biological_process	negative regulation of phagocytosis
A	0051224	biological_process	negative regulation of protein transport
A	0070062	cellular_component	extracellular exosome
A	0070273	molecular_function	phosphatidylinositol-4-phosphate binding
A	0070676	biological_process	intralumenal vesicle formation
A	0080025	molecular_function	phosphatidylinositol-3,5-bisphosphate binding
A	1901981	molecular_function	phosphatidylinositol phosphate binding
A	1905394	molecular_function	retromer complex binding
A	2000642	biological_process	negative regulation of early endosome to late endosome transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ARG70
A	SER72
A	LYS95
A	ARG118

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0000269|PubMed:12665801, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:25944712

Chain	Residue	Details
A	ALA2

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
A	ARG43

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER72

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS95

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