2MWX
The RING Domain of human Promyelocytic Leukemia Protein (PML)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | CYS57 |
| A | GLN59 |
| A | CYS60 |
| A | CYS77 |
| A | CYS80 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 202 |
| Chain | Residue |
| A | CYS72 |
| A | HIS74 |
| A | CYS88 |
| A | CYS91 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. ClHtLCsgCL |
| Chain | Residue | Details |
| A | CYS72-LEU81 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175 |
| Chain | Residue | Details |
| A | CYS57-GLN92 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS57 | |
| A | CYS60 | |
| A | CYS72 | |
| A | HIS74 | |
| A | CYS77 | |
| A | CYS80 | |
| A | CYS88 | |
| A | CYS91 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS65 |
