2MPF
Solution structure human HCN2 CNBD in the cAMP-unbound state
Functional Information from PROSITE/UniProt
| site_id | PS00888 |
| Number of Residues | 17 |
| Details | CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrEGTiGKkMYFIqhG |
| Chain | Residue | Details |
| A | ILE571-GLY587 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22006928, ECO:0007744|PDB:3U10 |
| Chain | Residue | Details |
| A | MET599 | |
| A | GLY608 | |
| A | GLU609 | |
| A | ILE610 | |
| A | CYS611 | |
| A | ARG618 | |
| A | THR619 | |
| A | ARG659 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKG/PRKG2 => ECO:0000250|UniProtKB:O88703 |
| Chain | Residue | Details |
| A | SER668 |
