2MMT
Lasso peptide-based integrin inhibitor: Microcin J25 variant with RGDF substitution of Gly12-Ile13-Gly14-Thr15
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Peptide: {"description":"Microcin J25","featureId":"PRO_0000002775","evidences":[{"source":"PubMed","id":"10092860","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Site: {"description":"Essential for permeation into bacteria","evidences":[{"source":"PubMed","id":"18632663","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Essential for permeation into bacteria and for RNAP inhibition","evidences":[{"source":"PubMed","id":"18632663","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Isoglutamyl glycine isopeptide (Gly-Glu)","evidences":[{"source":"PubMed","id":"14531661","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14531690","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14531691","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
