2MMT
Lasso peptide-based integrin inhibitor: Microcin J25 variant with RGDF substitution of Gly12-Ile13-Gly14-Thr15
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | SITE: Essential for permeation into bacteria => ECO:0000269|PubMed:18632663 |
| Chain | Residue | Details |
| A | GLY4 | |
| A | PRO7 | |
| A | PHE10 | |
| A | PHE19 | |
| A | TYR20 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Essential for permeation into bacteria and for RNAP inhibition => ECO:0000269|PubMed:18632663 |
| Chain | Residue | Details |
| A | TYR9 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Isoglutamyl glycine isopeptide (Gly-Glu) => ECO:0000269|PubMed:14531661, ECO:0000269|PubMed:14531690, ECO:0000269|PubMed:14531691 |
| Chain | Residue | Details |
| A | GLY1 | |
| A | GLU8 |
