2MMO

Solution Structure of the oxidised Thioredoxin from Plasmodium falciparum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0015035	molecular_function	protein-disulfide reductase activity

Functional Information from PROSITE/UniProt

site_id	PS00194
Number of Residues	19
Details	THIOREDOXIN_1 Thioredoxin family active site. IVdFFaeWCGPCKrIapfY

Chain	Residue	Details
A	ILE22-TYR40

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P10599

Chain	Residue	Details
A	CYS30
A	CYS33

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Deprotonates C-terminal active site Cys => ECO:0000305

Chain	Residue	Details
A	ASP24

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Contributes to redox potential value => ECO:0000305

Chain	Residue	Details
A	GLY31
A	PRO32

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