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2MJW

Structural Insights into Calcium Bound S100P - V Domain of the receptor for advanced glycation end products (RAGE) Complex

Functional Information from GO Data
ChainGOidnamespacecontents
B0000287molecular_functionmagnesium ion binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005886cellular_componentplasma membrane
B0008284biological_processpositive regulation of cell population proliferation
B0010033biological_processresponse to organic substance
B0016020cellular_componentmembrane
B0016529cellular_componentsarcoplasmic reticulum
B0031528cellular_componentmicrovillus membrane
B0034774cellular_componentsecretory granule lumen
B0042803molecular_functionprotein homodimerization activity
B0042995cellular_componentcell projection
B0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
B0043542biological_processendothelial cell migration
B0044548molecular_functionS100 protein binding
B0045296molecular_functioncadherin binding
B0046872molecular_functionmetal ion binding
B0046914molecular_functiontransition metal ion binding
B0048306molecular_functioncalcium-dependent protein binding
B0048471cellular_componentperinuclear region of cytoplasm
B0050786molecular_functionRAGE receptor binding
B0070062cellular_componentextracellular exosome
D0000287molecular_functionmagnesium ion binding
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005886cellular_componentplasma membrane
D0008284biological_processpositive regulation of cell population proliferation
D0010033biological_processresponse to organic substance
D0016020cellular_componentmembrane
D0016529cellular_componentsarcoplasmic reticulum
D0031528cellular_componentmicrovillus membrane
D0034774cellular_componentsecretory granule lumen
D0042803molecular_functionprotein homodimerization activity
D0042995cellular_componentcell projection
D0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
D0043542biological_processendothelial cell migration
D0044548molecular_functionS100 protein binding
D0045296molecular_functioncadherin binding
D0046872molecular_functionmetal ion binding
D0046914molecular_functiontransition metal ion binding
D0048306molecular_functioncalcium-dependent protein binding
D0048471cellular_componentperinuclear region of cytoplasm
D0050786molecular_functionRAGE receptor binding
D0070062cellular_componentextracellular exosome
Functional Information from PROSITE/UniProt
site_idPS00303
Number of Residues22
DetailsS100_CABP S-100/ICaBP type calcium binding protein signature. LLkdLDangDaqvDFsEFivFV
ChainResidueDetails
BLEU57-VAL78

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues16
DetailsBINDING: BINDING => ECO:0000305
ChainResidueDetails
BTHR25
DTHR121
DGLU126
DASP156
DASN158
DASP160
DGLN162
DGLU167
BTHR27
BGLU32
BASP62
BASN64
BASP66
BGLN68
BGLU73
DTHR119

218853

PDB entries from 2024-04-24

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