2MJW

Structural Insights into Calcium Bound S100P - V Domain of the receptor for advanced glycation end products (RAGE) Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000287	molecular_function	magnesium ion binding
B	0005509	molecular_function	calcium ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0016020	cellular_component	membrane
B	0031528	cellular_component	microvillus membrane
B	0034774	cellular_component	secretory granule lumen
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0042995	cellular_component	cell projection
B	0043542	biological_process	endothelial cell migration
B	0045296	molecular_function	cadherin binding
B	0046872	molecular_function	metal ion binding
B	0046914	molecular_function	transition metal ion binding
B	0048306	molecular_function	calcium-dependent protein binding
B	0070062	cellular_component	extracellular exosome
D	0000287	molecular_function	magnesium ion binding
D	0005509	molecular_function	calcium ion binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0016020	cellular_component	membrane
D	0031528	cellular_component	microvillus membrane
D	0034774	cellular_component	secretory granule lumen
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0042995	cellular_component	cell projection
D	0043542	biological_process	endothelial cell migration
D	0045296	molecular_function	cadherin binding
D	0046872	molecular_function	metal ion binding
D	0046914	molecular_function	transition metal ion binding
D	0048306	molecular_function	calcium-dependent protein binding
D	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00303
Number of Residues	22
Details	S100_CABP S-100/ICaBP type calcium binding protein signature. LLkdLDangDaqvDFsEFivFV

Chain	Residue	Details
B	LEU57-VAL78

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	186
Details	Domain: {"description":"Ig-like V-type"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	70
Details	Domain: {"description":"EF-hand 1","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	70
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	16
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---