2MJV
Solution structures of second bromodomain of Brd4 with di-acetylated Twist peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR CHAIN A OF TWIST-RELATED PROTEIN 1 |
| Chain | Residue |
| B | ALA371 |
| B | ASP389 |
| B | ILE393 |
| B | ASN428 |
| B | CYS429 |
| B | LYS431 |
| B | TYR432 |
| B | ASN433 |
| B | PRO434 |
| B | HIS437 |
| B | GLU438 |
| B | TRP374 |
| B | VAL439 |
| B | MET442 |
| B | PRO375 |
| B | PHE376 |
| B | PRO379 |
| B | VAL380 |
| B | ASP381 |
| B | LEU385 |
| B | LEU387 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 109 |
| Details | Domain: {"description":"Bromo 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Acetylated histone binding","evidences":[{"source":"PubMed","id":"22464331","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
