2MJ0

Spatial structure of P33A mutant of non-conventional toxin WTX from Naja kaouthia

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity

Functional Information from PROSITE/UniProt

site_id	PS00272
Number of Residues	21
Details	SNAKE_TOXIN Snake toxins signature. GCadtCPvgkpyemie.CCstD

Chain	Residue	Details
A	GLY141-ASP161

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Site: {"description":"Important for interaction with human M1/CHRM1 and M3/CHRM3 mAChR, and muscle (Torpedo) and neuronal (alpha-7/CHRNA7) nAChR","evidences":[{"source":"PubMed","id":"26242733","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27343701","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Important for interaction with human M1/CHRM1 and M3/CHRM3 mAChR, and only weakly for muscle (Torpedo) nAChR","evidences":[{"source":"PubMed","id":"26242733","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27343701","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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