2MJ0

Spatial structure of P33A mutant of non-conventional toxin WTX from Naja kaouthia

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity

Functional Information from PROSITE/UniProt

site_id	PS00272
Number of Residues	21
Details	SNAKE_TOXIN Snake toxins signature. GCadtCPvgkpyemie.CCstD

Chain	Residue	Details
A	GLY141-ASP161

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Important for interaction with human M1/CHRM1 and M3/CHRM3 mAChR, and muscle (Torpedo) and neuronal (alpha-7/CHRNA7) nAChR => ECO:0000269|PubMed:26242733, ECO:0000269|PubMed:27343701

Chain	Residue	Details
A	ARG131
A	ARG132

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Important for interaction with human M1/CHRM1 and M3/CHRM3 mAChR, and only weakly for muscle (Torpedo) nAChR => ECO:0000269|PubMed:26242733, ECO:0000269|PubMed:27343701

Chain	Residue	Details
A	ARG137

---