2MH9

Resonance assignment of RQC domain of human Bloom syndrome protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0043138	molecular_function	3'-5' DNA helicase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Region: {"description":"DNA Holliday junction binding","evidences":[{"source":"PubMed","id":"24257077","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Region: {"description":"3' overhang DNA-binding","evidences":[{"source":"PubMed","id":"24816114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25901030","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4CGZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4O3M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"3' overhang DNA-binding","evidences":[{"source":"PubMed","id":"24816114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25901030","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4CGZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4O3M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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