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2ME6

NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens in complex with the DNA sequence CGACTAATTAGTCG

Functional Information from GO Data
ChainGOidnamespacecontents
A0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
A0003677molecular_functionDNA binding
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. IAhaLkLSevQVKIWFqNrrakwK
ChainResidueDetails
AILE40-LYS63

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues59
DetailsDNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108
ChainResidueDetails
ASER7-LYS66

237735

PDB entries from 2025-06-18

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