2MCG

THREE-DIMENSIONAL STRUCTURE OF A LIGHT CHAIN DIMER CRYSTALLIZED IN WATER. CONFORMATIONAL FLEXIBILITY OF A MOLECULE IN TWO CRYSTAL FORMS

Replaces:  1MCG

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0002250	biological_process	adaptive immune response
1	0002376	biological_process	immune system process
1	0003823	molecular_function	antigen binding
1	0005576	cellular_component	extracellular region
1	0005886	cellular_component	plasma membrane
1	0006955	biological_process	immune response
1	0019814	cellular_component	immunoglobulin complex
2	0002250	biological_process	adaptive immune response
2	0002376	biological_process	immune system process
2	0003823	molecular_function	antigen binding
2	0005576	cellular_component	extracellular region
2	0005886	cellular_component	plasma membrane
2	0006955	biological_process	immune response
2	0019814	cellular_component	immunoglobulin complex

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
1	TYR195-HIS201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Region: {"description":"Complementarity-determining-1","evidences":[{"source":"UniProtKB","id":"P01721","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	Region: {"description":"Framework-2","evidences":[{"source":"UniProtKB","id":"P01721","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Region: {"description":"Complementarity-determining-2","evidences":[{"source":"UniProtKB","id":"P01721","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	70
Details	Region: {"description":"Framework-3","evidences":[{"source":"UniProtKB","id":"P01721","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	42
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	16
Details	Region: {"description":"Complementarity-determining-3","evidences":[{"source":"UniProtKB","id":"P01721","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	24
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---