2M9W

Solution NMR Structure of Transcription Factor GATA-4 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR4783B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0008270	molecular_function	zinc ion binding
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 101

Chain	Residue
A	CYS13
A	CYS16
A	CYS34
A	CYS37

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Functional Information from PROSITE/UniProt

site_id	PS00344
Number of Residues	25
Details	GATA_ZN_FINGER_1 GATA-type zinc finger domain. CaNCqttt..TtlWRRnae.Gepv...CNAC

Chain	Residue	Details
A	CYS13-CYS37

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	ZN_FING: GATA-type 2 => ECO:0000255|PROSITE-ProRule:PRU00094

Chain	Residue	Details
A	CYS13-CYS37

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-methyllysine; by EZH2 => ECO:0000250|UniProtKB:Q08369

Chain	Residue	Details
A	LYS42

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